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1,1,2,2-Cyclopropanetetracarbonitrile, also known as CPT, is a highly toxic and reactive chemical compound with the molecular formula C6H4N4. It is a colorless, crystalline solid that is soluble in water and organic solvents. CPT is a potent inhibitor of the enzyme dihydroorotate dehydrogenase (DHODH), which plays a crucial role in the synthesis of pyrimidine nucleotides. Due to its ability to disrupt the synthesis of DNA and RNA, CPT has been studied for its potential use as an antiviral and anticancer agent. However, its high toxicity and potential for causing severe side effects have limited its clinical application. The compound is also used as a chemical intermediate in the synthesis of other pharmaceuticals and agrochemicals. Due to its hazardous nature, handling and storage of 1,1,2,2-Cyclopropanetetracarbonitrile require strict safety measures and adherence to proper guidelines.

2424-32-0

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2424-32-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2424-32-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,4,2 and 4 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 2424-32:
(6*2)+(5*4)+(4*2)+(3*4)+(2*3)+(1*2)=60
60 % 10 = 0
So 2424-32-0 is a valid CAS Registry Number.
InChI:InChI=1/C7H2N4/c8-2-6(3-9)1-7(6,4-10)5-11/h1H2

2424-32-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name cyclopropane-1,1,2,2-tetracarbonitrile

1.2 Other means of identification

Product number -
Other names 1,1,2,2-Tetracyanocyclopropan

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2424-32-0 SDS

2424-32-0Downstream Products

2424-32-0Relevant academic research and scientific papers

Electrochemical transformation of malononitrile and carbonyl compounds into functionally substituted cyclopropanes: Electrocatalytic variant of the Wideqvist reaction

Elinson, Michail N.,Feducovich, Sergey K.,Lizunova, Tatiana L.,Nikishin, Gennady I.

, p. 3063 - 3069 (2007/10/03)

Electrolysis of malononitrile and carbonyl compounds in the presence of alkali metal halides in an undivided cell results in the formation of substituted 1,1,2,2-tetracyanocyclopropanes in 60-90% yield. This electrocatalytic variant of the Wideqvist reaction using malononitrile instead of bromomalonitrile was successfully performed. Electrocatalytic transformation of substituted 1,1,2,2-tetracyanocyclopropanes in methanol or ethanol in an undivided cell leads to substituted 2-amino-4,4-dialkoxy-1,5- dicyano-3-azabicyclo[3.1.0]hex-2-enes in 70-95% yields after 0.05-0.10 F/mol of electricity has been passed. (C) 2000 Elsevier Science Ltd.

The reaction of aliphatic diazo compounds with highly electrophilic ethylene derivatives

Eichenauer, Ulrich,Huisgen, Rolf,Mitra, Abhijit,Moran, Joaquin Rodriguez

, p. 129 - 132 (2007/10/02)

The cycloadditions of diazoacetic ester and diazomethane to tetracyanoethylene and ethylenetetracarboxylic ester, as well as reactions of the pyrazolines formed were investigated. In contrast to an earlier report, diazoacetic ester adds to the CC double bond of tetracyanoethylene.

1,3-Dipolar Cycloadditions, 92. - Reactions of Aliphatic Diazo Compounds with Fourfold Acceptor-Substituted Ethylenes

Huisgen, Rolf,Eichenauer, Ulrich,Langhals, Elke,Mitra, Abhijit,Moran, Joaquin Rodriguez

, p. 153 - 158 (2007/10/02)

In contrast to a literature report, diazomethane and diazoacetic ester add to the CC double bond of tetracyanoethylene and ethylenetetracarboxylic ester.The behavior of the 1- and 2-pyrazolines deviates from the rule.

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