2424-62-6Relevant articles and documents
Order-disorder transitions in Langmuir-Blodgett films. II. IR studies of the polymerization of Cd-octadecylfumarate and Cd-octadecylmaleate
Rabe, J. P.,Rabolt, J. F.,Brown, C. A.,Swalen, J. D.
, p. 4096 - 4102 (1986)
The two isomeric compounds, octadecylfumaric acid and octadecylmaleic acid (C18H37OCOCH = CHCOOH) have been synthesized, and Langmuir-Blodgett films of their cadmium salts have been studied by means of transmission and grazing incidence reflection infrared spectroscopy.These measurements provided information about the orientation of molecular segments relative to the substrate surface as well as about the lateral packing of the chains in the unit cell.A structural change of the maleate film was revealed at elevated temperatures.Polymerization of the films was brought about by either UV irradiation or thermal treatment and was followed spectroscopically as a function of exposure time.By comparison with films polymerized on the water surface of a Langmuir trough, it was concluded that the molecular structure is independent of where the polymerization occurs.Interestingly, upon polymerization on the water surface the fumarate undergoes an expansion at constant surface pressure whereas the maleate contracts.A mixture of fumarate and maleate in the ratio of 1 to 3, however, forms a two dimensional solution and preserves its area upon polymerization, a critical feature required for the fabrication of crack free Langmuir-Blodgett films polymerized on solid substrates.
DRUGS AND COMPOSITIONS FOR THE TREATMENT OF OCULAR DISORDERS
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Page/Page column 245; 384, (2018/10/19)
The present invention provides new prodrugs of therapeutically active compounds, including oligomeric prodrugs, and compositions to treat medical disorders, for example glaucoma, a disorder or abnormality related to an increase in intraocular pressure (IOP), a disorder requiring neuroprotection, age-related macular degeneration, or diabetic retinopathy.
Epoxidation of monomaleate with hydrogen peroxide catalyzed by [π-C 5H5N(CH2)15CH3] 3PO4(WO3)4
Zhang, Zhiliang,Li, Tianduo
experimental part, p. 3417 - 3423 (2011/10/04)
In the study, epoxidation of dodecanol monomaleate, hexadecanol monomaleate, and octadecanol monomaleate were carried out using [π-C 5H5N(CH2)15CH3] 3PO4(WO3)4 as phase-transfer catalyst with 30% hydrogen peroxide as oxidant. The experimental results showed that [π-C5H5N(CH2)15CH 3]3PO4(WO3)4 had excellent catalytic effect on translating C=C double-bond into an epoxy group and had a good yield rate. The synthesized epoxides of decanol monomaleate, hexadecanol monomaleate, and octadecanol monomaleate have enormous potential application in organic synthesis, and they could be readily transformed into various synthetically useful intermediates or final products in many fields of chemistry.