2424-62-6

Usage

Uses

Used in Humidity Sensor Applications:
Monostearyl Maleate (100 MG) is used as a component in the synthesis of inorganic-organic hybrid nanowires for humidity sensors. Its unique properties contribute to the efficient functioning of these sensors by enhancing their sensitivity and stability in detecting changes in humidity levels.
Additionally, Monostearyl Maleate (100 MG) has other potential applications in different industries, such as:
Used in Pharmaceutical Industry:
Monostearyl Maleate (100 MG) is used as an excipient in the formulation of pharmaceutical products, particularly in the development of emulsions, creams, and ointments. Its emulsifying and stabilizing properties help in creating stable and consistent formulations, ensuring the effective delivery of active ingredients.
Used in Cosmetics Industry:
In the cosmetics industry, Monostearyl Maleate (100 MG) is used as an ingredient in various cosmetic products, such as lotions, creams, and makeup formulations. Its ability to improve the texture, consistency, and stability of these products makes it a valuable addition to the formulation process.
Used in Food Industry:
Monostearyl Maleate (100 MG) is also utilized in the food industry as an additive to improve the texture, stability, and shelf life of certain food products. Its emulsifying properties help in creating stable emulsions, which are essential for the production of various food items.

InChI:InChI=1/C22H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20-26-22(25)19-18-21(23)24/h18-19H,2-17,20H2,1H3,(H,23,24)/b19-18-

Upstream product

• 108-31-6 maleic anhydride 
• 112-92-5 1-octadecanol 

Relevant academic research and scientific papers

Order-disorder transitions in Langmuir-Blodgett films. II. IR studies of the polymerization of Cd-octadecylfumarate and Cd-octadecylmaleate

The two isomeric compounds, octadecylfumaric acid and octadecylmaleic acid (C18H37OCOCH = CHCOOH) have been synthesized, and Langmuir-Blodgett films of their cadmium salts have been studied by means of transmission and grazing incidence reflection infrared spectroscopy.These measurements provided information about the orientation of molecular segments relative to the substrate surface as well as about the lateral packing of the chains in the unit cell.A structural change of the maleate film was revealed at elevated temperatures.Polymerization of the films was brought about by either UV irradiation or thermal treatment and was followed spectroscopically as a function of exposure time.By comparison with films polymerized on the water surface of a Langmuir trough, it was concluded that the molecular structure is independent of where the polymerization occurs.Interestingly, upon polymerization on the water surface the fumarate undergoes an expansion at constant surface pressure whereas the maleate contracts.A mixture of fumarate and maleate in the ratio of 1 to 3, however, forms a two dimensional solution and preserves its area upon polymerization, a critical feature required for the fabrication of crack free Langmuir-Blodgett films polymerized on solid substrates.

DRUGS AND COMPOSITIONS FOR OCULAR DELIVERY

New prodrugs of therapeutically active compounds, including oligomeric prodrugs of ethacrynic acid, and compositions to treat medical disorders, for example glaucoma, a disorder or abnormality related to an increase in intraocular pressure (IOP), a disorder requiring neuroprotection, age-related macular degeneration, or diabetic retinopathy. Also a method for the controlled administration of timolol to a patient in need thereof, such as a human, comprising administering a prodrug of timolol in a microparticle in vivo, wherein the timolol prodrug containing microparticle exhibits in vitro drug release kinetics in an aqueous solution at a pH between 6-8 at body temperature of a substantially consistent release of at least 60% timolol itself by molar ratio to the prodrug of timolol or an intermediate metabolite thereof over at least 100 days.

DRUGS AND COMPOSITIONS FOR THE TREATMENT OF OCULAR DISORDERS

The present invention provides new prodrugs of therapeutically active compounds, including oligomeric prodrugs, and compositions to treat medical disorders, for example glaucoma, a disorder or abnormality related to an increase in intraocular pressure (IOP), a disorder requiring neuroprotection, age-related macular degeneration, or diabetic retinopathy.

A commonly used method for preparation of supplementary material

The invention relates to a preparation method of a common pharmaceutical preparation auxiliary material sodium stearyl fumarate. An organic alkaline catalyst is utilized to lower the reaction temperature, thereby obtaining the high-quality product at high yield. By selecting the reaction conditions, the product satisfying the quality requirements can be prepared, and satisfies the requirements for pharmaceutical preparations. The method is simple to operate, has the advantages of high safety and low cost, and is suitable for industrial production.

Epoxidation of monomaleate with hydrogen peroxide catalyzed by [π-C 5H5N(CH2)15CH3] 3PO4(WO3)4

In the study, epoxidation of dodecanol monomaleate, hexadecanol monomaleate, and octadecanol monomaleate were carried out using [π-C 5H5N(CH2)15CH3] 3PO4(WO3)4 as phase-transfer catalyst with 30% hydrogen peroxide as oxidant. The experimental results showed that [π-C5H5N(CH2)15CH 3]3PO4(WO3)4 had excellent catalytic effect on translating C=C double-bond into an epoxy group and had a good yield rate. The synthesized epoxides of decanol monomaleate, hexadecanol monomaleate, and octadecanol monomaleate have enormous potential application in organic synthesis, and they could be readily transformed into various synthetically useful intermediates or final products in many fields of chemistry.

Process for producing an unsymmetrical diester of α, β-unsaturated dicarboxylic acid

A process for producing a colorless unsymmetrical-diester of maleic acid, useful as a raw material of an emulsifier for emulsion polymerization and as a modifier for a polymer, which comprises: (1) reacting maleic anhydride with a monohydric alcohol in the presence of an inert organic solvent, in a molar ratio of 1:(1.0-1.2) to obtain maleic acid mono ester containing substantially no unreacted maleic anhydride, and (2) reacting said monoester with an alkenyl halide in the presence of a tertiary amine and water, in a molar ratio of said monoester:water of 1:(0.01-0.20).