24247-68-5

Usage

Uses

Used in Pharmaceutical Industry:
1-Oxa-3-azaspiro[4.5]decan-2-one is used as a building block for the synthesis of other biologically active compounds due to its unique structure. It has potential applications in the development of pharmaceutical drugs.
Used in Medicinal Chemistry Research:
1-Oxa-3-azaspiro[4.5]decan-2-one is used as a research compound for studying its potential therapeutic properties. It has been investigated for its potential as a sedative and anxiolytic agent, as well as its anticonvulsant properties, making it a promising candidate for further exploration in medicinal chemistry.

Upstream product

• 412035-04-2 (1-hydroxy-cyclohexyl)-acetic acid hydrazide 
• 26225-83-2 1-oxa-3-aza-spiro[4.5]dec-2-en-2-ylamine 
• 81467-26-7 3-<(1-Hydroxycyclohexyl)methyl>-1,4,2-dioxazol-5-on 
• 1659-31-0 2,2'-dipyridyl carbonate 
• 108-94-1 cyclohexanone 
• 5326-50-1 (1-hydroxycyclohexyl)acetic acid ethyl ester 
• 40894-17-5 1-(2-hydroxyethyl)cyclohexanol 
• 26228-58-0 1-aminomethyl-cyclohexanol; acetate 

Downstream Products

• 37150-63-3 1-(acetamidomethyl)cyclohexanol 
• 16113-08-9 3-benzyl-1-oxa-3-aza-spiro[4.5]decan-2-one 
• 1012785-40-8 3-(4-iodo-benzyl)-1-oxa-3-aza-spiro[4.5]decan-2-one 

Relevant academic research and scientific papers

Synthesis of oxazolidin-2-ones and imidazolidin-2-ones directly from 1,3-diols or 3-amino alcohols using iodobenzene dichloride and sodium azide

A general and efficient method for the synthesis of oxazolidin-2-ones and imidazolidin-2-ones directly from 1,3-diols and 3-amino alcohols has been developed using the same reagent combination of iodobenzene dichloride (PhICl2) and sodium azide (NaN3).

SPIRO-OXAZOLIDINONE COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR POTENTIATORS

Compounds in accord with Formula (I): wherein R1, L, A, B, D, E, m, n, x and y are as defined in the description, processes for the preparation of such compounds and to new intermediates employed in the preparation thereof, pharmaceutical compositions containing such compounds, and the use of such compounds in therapy and for the treatment of diseases mentioned in the specification.

Cyclic Carbonylation of 3-Hydroxycarbohydroxamic Acids with 1,1'-Carbonyldiimidazole

The reaction of 3-hydroxycarbohydroxamic acids 3 with 1,1'-carbonyldiimidazole produces as a function of the substitution of 3 heterocycles of type 1, 4, and 5.In the presence of imidazole the 3-(2-hydroxyalkyl)-1,4,2-dioxazol-5-ones 1 undergo rearrangeme