24251-07-8Relevant academic research and scientific papers
Palladium-catalyzed phosphine-free direct C-H arylation of benzothiophenes and benzofurans involving MIDA boronates
Wang, Zhiwei,Li, Yabo,Yan, Beiqi,Huang, Mengmeng,Wu, Yangjie
supporting information, p. 531 - 536 (2015/03/04)
With high regioselectivity, a series of benzoheterocyclic compounds were synthesized via palladiium-catalyzed phosphine-free C-H arylation of benzothiophenes/benzofurans with aryl MIDA boronates at 30-50 °C in moderate to excellent yields. MIDA boronates were used in C-H arylation of heterocycles for the first time. Under the optimal conditions, the benzothiophenes could be transformed into the β-arylbenzothiophenes, and the benzofurans gave only α-aryl-substituted products.
Pd-catalyzed β-selective direct C-H bond arylation of thiophenes with aryltrimethylsilanes
Funaki, Kenji,Sato, Tetsuo,Oi, Shuichi
supporting information, p. 6186 - 6189 (2013/02/23)
Direct arylation of thiophenes and benzothiophenes with aryltrimethylsilanes was effectively catalyzed by PdCl2(MeCN) 2 in the presence of CuCl2 as an oxidant. The reaction preferentially occurred at the β-position of both
