242792-64-9Relevant academic research and scientific papers
Synthesis of Hydroxamic Esters via Alkoxyaminocarbonylation of β-Dicarbonyl Compounds
Hanessian, Stephen,Johnstone, Shawn
, p. 5896 - 5903 (1999)
N-t-Butoxycarbonyl-O-sulfonyl-substituted hydroxylamines react with soft enolates to yield O-t-butoxycarbonylamino derivatives rather than the expected Boc-protected amino acids. The reaction is limited to enolates of β-dicarbonyl compounds. Decarboxylation of the resultant tricarbonyl compound affords malonyl α-alkyl O-t-butoxycarbonylamino derivatives.
