24310-41-6

Usage

Uses

Used in Pesticide Synthesis:
3-Benzotriazin-4(3h)-one,3-(chloromethyl)-2 is used as an intermediate in the synthesis of Guthoxon (G855650), an organophosphorus anticholinesterase pesticide. Its role in the production process is essential for creating a compound that effectively targets and inhibits the acetylcholinesterase enzyme in pests, leading to their paralysis and eventual death. This application is particularly relevant in the agricultural industry, where Guthoxon is employed to protect crops from damage caused by various insect species.

InChI:InChI=1/C8H6ClN3O/c9-5-12-8(13)6-3-1-2-4-7(6)10-11-12/h1-4H,5H2

Upstream product

• 24310-40-5 3-(hydroxymethyl)benzotriazin-4(3H)-one 
• 50-00-0 formaldehyd 
• 90-16-4 1,2,3-benzotriazin-4(3H)-one 
• 28144-70-9 anthranilic acid amide 

Downstream Products

• 2642-71-9 azinphos-ethyl 
• 86-50-0 Azinphos-methyl 

Relevant academic research and scientific papers

Production of High-Affinity Monoclonal Antibodies for Azinphos-methyl from a Hapten Containing Only the Aromatic Moiety of the Pesticide

Keywords: Azinphos; Guthion; hapten synthesis; monoclonal antibodies; ELISA; phosmet

A benzene and three qinqin alkone of 1, 4 - pentadiene -3 - ketone derivatives, preparation method and use thereof

The invention discloses a 1,4-pentadiene-3-ketone derivative containing benzotriazinone. The 1,4-pentadiene-3-ketone derivative containing benzotriazinone is characterized by having the general formula as shown in the specification, wherein R1 is phenyl, substituted phenyl (p-fluorophenyl, p-chlorophenyl, o-chlorophenyl, 2-methyoxyphenyl, 4-methyoxyphenyl, 4-methylphenyl, 2,4-dimethyoxyphenyl, 3,4-dimethyoxyphenyl, cinnamaldehyde group, 3-nitrophenyl, 2-chloro-5-nitrophenyl and the like), heterocyclic group (furyl, thienyl, 2-pyridyl, 3-pyridyl, 4-pyridyl, pyrryl and the like) or substituted aromatic heterocyclic group (5-methyl thiazole, 5-methyl-2-thienyl, 4-bromo-2-thienyl and the like), and R2 is a hydrogen atom, methyl (ethyl), methoxyl (ethyoxyl) and the like. The compound disclosedby the invention has relatively high inhibiting activity for citrus canker bacteria, ralstonia solanacearum and tobacco mosaic viruses so as to be used for preparing an agricultural bactericide and anantiviral agent.

Synthesis, antibacterial, and antiviral activities of novel penta-1,4-dien-3-one derivatives containing a benzotriazin-4(3H)-one moiety

A series of penta-1,4-dien-3-one containing a benzotriazin-4(3H)-one moiety were prepared and evaluated for their antibacterial and antiviral activities. Bioassays indicated that some compounds exhibited good antibacterial and antiviral activities. Among them, the EC50 values of compound 6d against Xanthomonas axonopodis pv. citri and compound 6l against Ralstonia solanacearum were, respectively, 22.45 and 34.77?μg/mL, which were better than that of thiodiazole copper (51.35 and 87.26?μg/mL, respectively). Meanwhile, some title compounds were found to show remarkable antiviral activities against tobacco mosaic virus (TMV). These results indicated that penta-1,4-dien-3-one derivatives containing benzotriazin-4(3H)-one moiety could play significant roles in searching for novel agrochemicals.

Synthesis and photophysical properties of N-styrylazinones

(Chemical Equation Presented) N-Styrylazinones and 1-styrylbenzotriazine were synthesized, and their photophysical properties were investigated. (Z)- and/or (E)-N-Styrylazinones (or azine) 4 were prepared from the corresponding heterocycles 1 and benzaldehyde (3) by four methods. The absorption maxima of (Z)- and/or (E)-4a - 4j were measured in four solvents. Their absorption maxima showed a moderate dependence upon solvents. The absorption maxima of (Z)-isomers were blue-shifted as compared the corresponding (E)-isomers. Emission maxima, fluorescence band half-widths, 0,0 transition energies, Stokes shifts, and quantum yields of (Z)- and/or (E)-4a, 4b, 4d, 4e and 4j were measured in organic solvents. The fluorescence spectra show moderate solvatochroism. The fluorescence properties of N-styrylheterocycles vary with every heterocycles.