24310-41-6

Basic information

• Product Name: 3-benzotriazin-4(3h)-one,3-(chloromethyl)-2
• Synonyms: 3-(chloromethyl)-4-ketobenz-1,2,3-triazine;3-benzotriazin-4(3h)-one,3-(chloromethyl)-2;1,2,3-Benzotriazin-4(3H)-one, 3-(chloromethyl)-;3-Chloromethyl-4-keto-1,2,3-benzotriazine;Einecs 246-152-3
• CAS NO: 24310-41-6
• Molecular Formula: C₈H₆ClN₃O
• Molecular Weight: 195.60574
• EINECS: 246-152-3
• Mol File: 24310-41-6.mol
• Article Data: 4

Chemical Properties

• Melting Point: 127-128 °C(Solv: ethyl ether (60-29-7); hexane (110-54-3))
• Boiling Point: 317.3°Cat760mmHg
• Flash Point: 145.7°C
• Appearance: /
• Density: 1.49g/cm³
• Vapor Pressure: 0.000388mmHg at 25°C
• Refractive Index: 1.684
• PKA: -2.60±0.20(Predicted)
• CAS DataBase Reference: 3-benzotriazin-4(3h)-one,3-(chloromethyl)-2(CAS DataBase Reference)
• NIST Chemistry Reference: 3-benzotriazin-4(3h)-one,3-(chloromethyl)-2(24310-41-6)
• EPA Substance Registry System: 3-benzotriazin-4(3h)-one,3-(chloromethyl)-2(24310-41-6)

Safety Data

• Hazardous Substances Data: 24310-41-6(Hazardous Substances Data)

Usage

Uses

3-(Chloromethyl)-1,2,3-benzotriazin-4(3H)-one is an intermediate used in synthesizing Guthoxon (G855650), an organophosphorus anticholinesterase pesticide.

InChI:InChI=1/C8H6ClN3O/c9-5-12-8(13)6-3-1-2-4-7(6)10-11-12/h1-4H,5H2

Upstream product

• 50-00-0 formaldehyd 
• 90-16-4 1,2,3-benzotriazin-4(3H)-one 
• 28144-70-9 anthranilic acid amide 
• 24310-40-5 3-(hydroxymethyl)benzotriazin-4(3H)-one 

Downstream Products

• 2642-71-9 azinphos-ethyl 
• 86-50-0 Azinphos-methyl 

Relevant articles and documents

Production of High-Affinity Monoclonal Antibodies for Azinphos-methyl from a Hapten Containing Only the Aromatic Moiety of the Pesticide

Keywords: Azinphos; Guthion; hapten synthesis; monoclonal antibodies; ELISA; phosmet

Synthesis, antibacterial, and antiviral activities of novel penta-1,4-dien-3-one derivatives containing a benzotriazin-4(3H)-one moiety

A series of penta-1,4-dien-3-one containing a benzotriazin-4(3H)-one moiety were prepared and evaluated for their antibacterial and antiviral activities. Bioassays indicated that some compounds exhibited good antibacterial and antiviral activities. Among them, the EC50 values of compound 6d against Xanthomonas axonopodis pv. citri and compound 6l against Ralstonia solanacearum were, respectively, 22.45 and 34.77?μg/mL, which were better than that of thiodiazole copper (51.35 and 87.26?μg/mL, respectively). Meanwhile, some title compounds were found to show remarkable antiviral activities against tobacco mosaic virus (TMV). These results indicated that penta-1,4-dien-3-one derivatives containing benzotriazin-4(3H)-one moiety could play significant roles in searching for novel agrochemicals.