243128-46-3 Usage
Uses
Used in Pharmaceutical Research and Development:
1-(4-Fluoro-2-nitrophenyl)piperazine is used as a building block for the synthesis of potential drugs due to its unique chemical structure and properties. Its versatility in chemical reactions allows for the creation of various drug candidates with different therapeutic potentials.
Used in Central Nervous System Disorders Treatment:
In the field of medicine, 1-(4-Fluoro-2-nitrophenyl)piperazine is used as a potential antipsychotic and anxiolytic agent. Its chemical structure lends itself to modulating neurotransmitter systems in the brain, which can be beneficial for the treatment of psychiatric conditions.
Used in Precursor Synthesis:
1-(4-Fluoro-2-nitrophenyl)piperazine also serves as a precursor in the synthesis of various other derivatives. These derivatives are further explored for their potential applications in research, including the development of new therapeutic agents and the study of biological mechanisms.
While the provided materials do not specify different industries for the uses of 1-(4-Fluoro-2-nitrophenyl)piperazine, the primary application is within the pharmaceutical and medicinal chemistry sectors, focusing on drug discovery and development. Further research may reveal additional applications in other industries as the compound's properties and potential uses are better understood.
Check Digit Verification of cas no
The CAS Registry Mumber 243128-46-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,4,3,1,2 and 8 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 243128-46:
(8*2)+(7*4)+(6*3)+(5*1)+(4*2)+(3*8)+(2*4)+(1*6)=113
113 % 10 = 3
So 243128-46-3 is a valid CAS Registry Number.
InChI:InChI=1/C10H12FN3O2/c11-8-1-2-9(10(7-8)14(15)16)13-5-3-12-4-6-13/h1-2,7,12H,3-6H2
243128-46-3Relevant academic research and scientific papers
Piperazine compounds and medicinal use thereof
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, (2008/06/13)
The present invention relates to a piperazine compound of the formula wherein R1and R2are each hydrogen, halogen, lower alkyl, lower alkoxy, amino, substituted amino, nitro, hydroxy or cyano, R3, R4and R5are each hydrogen, halogen, lower alkyl, lower alkoxy, nitro, amino, substituted amino or hydroxy, R6and R7are each hydrogen, lower alkyl, lower alkyl substituted by halogen, aralkyl, acyl or lower acyl substituted by halogen, R8and R9are each hydrogen or lower alkyl, Y is lower alkylene and the like, and ring A is phenyl, pyrimidyl, thiazolyl, pyridyl, pyrazyl or imidazolyl, a pharmaceutically acceptable salt thereof and pharmaceutical agents containing these compounds. The compound of the present invention has superior TNF-α production inhibitory effect and/or IL-10 production promoting effect, and, since it is free of or shows only strikingly reduced expression of an effect on the central nervous system, the compound is useful as a highly safe and superior TNF-α production inhibitor an/or IL-10 production promoter and is useful as an agent for the prophylaxis or treatment of various diseases caused by abnormal TNF-α production, diseases curable with IL-10, such as chronic inflammatory diseases, acute inflammatory diseases, inflammatory diseases due to infection, autoimmune diseases, allergic diseases, and TNF-α mediated diseases.
