243143-09-1

Basic information

• Product Name: 6-N-[(di-n-butylamino)methylene]-3'-{[N-(9-fluorenyl)methoxycarbonyl-L-alanyl]amino}-3'-deoxy-5'-O-(4,4'-dimethoxytrityl)-β-D-adenosine
• Synonyms: 6-N-[(di-n-butylamino)methylene]-3'-{[N-(9-fluorenyl)methoxycarbonyl-L-alanyl]amino}-3'-deoxy-5'-O-(4,4'-dimethoxytrityl)-β-D-adenosine
• CAS NO: 243143-09-1
• Molecular Weight: 1001.19
• Mol File: 243143-09-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-N-[(di-n-butylamino)methylene]-3'-{[N-(9-fluorenyl)methoxycarbonyl-L-alanyl]amino}-3'-deoxy-5'-O-(4,4'-dimethoxytrityl)-β-D-adenosine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-N-[(di-n-butylamino)methylene]-3'-{[N-(9-fluorenyl)methoxycarbonyl-L-alanyl]amino}-3'-deoxy-5'-O-(4,4'-dimethoxytrityl)-β-D-adenosine(243143-09-1)
• EPA Substance Registry System: 6-N-[(di-n-butylamino)methylene]-3'-{[N-(9-fluorenyl)methoxycarbonyl-L-alanyl]amino}-3'-deoxy-5'-O-(4,4'-dimethoxytrityl)-β-D-adenosine(243143-09-1)

Safety Data

• Hazardous Substances Data: 243143-09-1(Hazardous Substances Data)

Upstream product

• 35661-39-3 N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine 
• 1173243-10-1 3'-azido-6-N-[(di-n-butylamino)methylene]-3'-deoxy-5'-O-(4,4'-dimethoxytrityl)-β-D-adenosine 
• 131124-64-6 Fmoc-Ala-benzotriazolyl ester 

Downstream Products

• 1333992-36-1 6-N-[(di-n-butylamino)methylene]-3'-{[N-(9-fluorenyl)methoxycarbonyl-L-alanyl]amino}-3'-deoxy-5'-O-(4,4'-dimethoxytrityl)-2'-O-[1,6-dioxo-6-(pentafluorophenyloxy)hexyl]-β-D-adenosine 

Relevant articles and documents

Functionalized polystyrene supports for solid-phase synthesis of glycyl-, alanyl-, and isoleucyl-RNA conjugates as hydrolysis-resistant mimics of peptidyl-tRNAs

RNA-peptide conjugates that mimic amino acid-charged tRNAs and peptidyl-tRNAs are of high importance for structural and functional investigations of ribosomal complexes. Here, we present the synthesis of glycyl-, alanyl-, and isoleucyladenosine modified solid supports that are eligible for the synthesis of stable 3′-aminoacyl- and 3′-peptidyl-tRNA termini with an amide instead of the natural ester linkage. The present work significantly expands the range of accessible peptidyl-tRNA mimics for ribosomal studies.