24332-24-9

Upstream product

• 15332-33-9 1-(hex-1-ynyl)cyclohexanol 
• 108-24-7 acetic anhydride 
• 108-94-1 cyclohexanone 
• 693-02-7 hex-1-yne 

Downstream Products

• 136291-75-3 1-cyclohexylidene-1-fluorohexan-2-one 
• 5452-52-8 2-cyclohexylidene-1-phenyl-1-ethanone 
• 1225432-41-6 1-bromo1-cyclohexylidene-n-hexan-2-one 
• 24332-28-3 (2-methyl-1-hexenylidene)-cyclohexane 

Relevant academic research and scientific papers

Domino gold-catalyzed rearrangement and fluorination of propargyl acetates

A combination of IPrAuNTf2 as catalyst in the presence of Selectfluor has been successfully used for the high yielding synthesis of α-fluoroenones via 1,3-acyloxy rearrangement of propargyl acetates followed by Csp2-F bond formation,

Efficient synthesis of e -α-haloenones through chemoselective alkyne activation over allene with triazole-Au catalysts

Figure presented The E-α-haloenones were prepared through a triazole-Au complex (TriA-Au) catalyzed propargyl acetate rearrangement and sequential allene halogenation. The reactions proceeded with only 1% catalyst loading, giving the challenging kinetic p

Gold-catalyzed efficient preparation of linear α-haloenones from propargylic acetates

Versatile linear α-iodo- and α-bromoenones are prepared efficiently from readily accessible propargylic acetates using 2 mol % of Au(PPh3)NTf2. This reaction is easy to execute and has broad substrate scope. Good to excellent Z-selectivities are observed in the cases of propargylic acetates derived from aliphatic aldehydes.

Gold-catalyzed efficient formation of α,β-unsaturated ketones from propargylic acetates

An efficient gold-catalyzed method for the preparation of α,β-unsaturated ketones from propargylic acetates has been developed. Under mild reaction conditions, β-monosubstituted enones were formed mostly with excellent E-selectivity. β,β-Disubstituted enones can be prepared from propargylic acetates derived from ketones. The high efficiency and mild nature of this reaction render it a viable alternative for the synthesis of α,β-unsaturated ketones.

Gold-catalyzed efficient preparation of linear α-lodoenones from propargylic acetates

Only 2 mol % of Au(PPh3)NTf2 is needed to convert readily accessible propargylic acetates into versatile linear α-iodoenones in good to excellent yields. This reaction is easy to execute and has broad substrate scope. Good to excellent Z-selectivities are observed in the cases of aliphatic propargylic acetates derived from aldehydes.