24333-41-3

Basic information

• Product Name: Nonanediamide, N,N'-bis(phenylmethyl)-
• CAS NO: 24333-41-3
• Molecular Formula: C23H30N2O2
• Molecular Weight: 366.503
• Mol File: 24333-41-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Nonanediamide, N,N'-bis(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Nonanediamide, N,N'-bis(phenylmethyl)-(24333-41-3)
• EPA Substance Registry System: Nonanediamide, N,N'-bis(phenylmethyl)-(24333-41-3)

Safety Data

• Hazardous Substances Data: 24333-41-3(Hazardous Substances Data)

Upstream product

• 624-17-9 diethyl azelate 
• 100-46-9 benzylamine 
• 123-99-9 azelaic acid 
• 123-98-8 azelaoyl chloride 

Downstream Products

• 109-31-9 di-hexyl azelate 

Relevant articles and documents

Nickel-Catalyzed Esterification of Aliphatic Amides

Recent studies have demonstrated that amides can be used in nickel-catalyzed reactions that lead to cleavage of the amide C?N bond, with formation of a C?C or C?heteroatom bond. However, the general scope of these methodologies has been restricted to amides where the carbonyl is directly attached to an arene or heteroarene. We now report the nickel-catalyzed esterification of amides derived from aliphatic carboxylic acids. The transformation requires only a slight excess of the alcohol nucleophile and is tolerant of heterocycles, substrates with epimerizable stereocenters, and sterically congested coupling partners. Moreover, a series of amide competition experiments establish selectivity principles that will aid future synthetic design. These studies overcome a critical limitation of current Ni-catalyzed amide couplings and are expected to further stimulate the use of amides as synthetic building blocks in C?N bond cleavage processes.