24338-62-3Relevant academic research and scientific papers
DITERPENES FROM SIDERITIS INFERNALIS
Fernandez, Concepcion,Fraga, Braulio M.,Hernandez, Melchor G.
, p. 2573 - 2576 (1986)
Key Word Index - Sideritis infernalis; Labiatae; diterpenes; ent-kaurene; episinfernal; sinfernal; sinfernol; epoxysinfernol; canditriol.Five new ent-kaurene diterpenes, episinfernal, sinfernal, sinfernol, epoxysinfernol and canditriol, and the known one, candol B, candicandiol and candidiol, have been isolated from the aerial parts of Sideritis infernalis.
THE BIOTRANSFORMATION OF TWO ENT-15β,16β-EPOXY-KAURANE DERIVATIVES BY GIBBERELLA FUJIKUROI
Fraga, Braulio M.,Hernandez, Melchor G.,Garcia-Tellado, Fernando,Gonzalez, Pedro,Peralest, Aurea
, p. 133 - 138 (2007/10/02)
The microbiological transformation of the diterpene ent-15β,16β-epoxy-14α-hydroxykaurane into ent-14α,15β-dihydroxy-11α,16α-epoxykaurane, ent-7α,14α,15β-trihydroxy-11α,16α-epoxykaurane and ent-7β,14α,15β-trihydroxy-11α,16α-epoxykaurane has been carried out using the fungus Gibberella fujikuroi.The incubation with this fungus of sideroxol (ent-7α,18-dihydroxy-15β,16β-epoxykaurane) gave as main products ent-7α,15β,18-trihydroxy-11α,16α-epoxykaurane and ent-7α,13,18-trihydroxy-15α,16α-epoxykaurane.Some of these compounds were identified as their acetate derivatives.The presence of the 15α,16α-epoxy group in these two substrates inhibits transformations involving oxidation at C-9 and favours the hydroxylation at C-11(β).
THE MICROBIOLOGICAL TRANSFORMATION OF SOME ENT-7α,15β-DIHYDROXYKAURENE DERIVATIVES BY GIBBERELLA FUJIKUROI
Fraga, Braulio M.,Hernandez, Melchor G.,Gonzales, Pedro
, p. 2567 - 2571 (2007/10/02)
The microbiological transformation by the fungus Gibberella fujikuroi of ent-7α,15β-dihydroxy-kaur-16-ene gave ent-7α,15β,19-trihydroxy-kaur-16-ene, ent-7α,11α,15β-trihydroxykaur-16-ene, ent-7α,11α,15β,16β,17-pentahydroxy-kaurane and ent-7α,11α,13,15β-tetrahydroxy-kaur-16-ene. ent-7α,15β,18-Trihydroxy-kaur-16-ene (eubotriol) afforded ent-7α,11α,15β,18-tetrahydroxy-kaur-16-ene, ent-7α,15β,18,19-tetrahydroxy-kaur-16-ene, ent-7α,17,18-trihydroxy-15β,16β-epoxy-kaurane (epoxysideritriol), and ent-7α,17,18,19-tetrahydroxy-kaur-15-ene.The last three compounds were identified as their acetate derivatives.Key Word Index - Gibberella fujikuroi; microbiological transformations; diterpenes; ent-7α,15β-dihydroxy-kaur-16-ene; eubotriol.
