243462-18-2Relevant academic research and scientific papers
Synthesis of β-aryl ketones by heck arylation of allylic alcohols catalysed by a MCM-41-supported bidentate nitrogen palladium complex
Huang, Yixiang,Wang, Pingping,Liu, Jiaqin,Cai, Mingzhong
, p. 333 - 336 (2013)
The Heck arylation reaction of aryl iodides with allylic alcohols catalysed by an mesoporous silica (MCM-41)-supported bidentate nitrogen palladium complex [MCM-41-2N-Pd(OAc)2] proceeded smoothly in the presence of tetrabutylammonium chloride (TBAC) in DMF to afford β-aryl ketones in good to excellent yields. This heterogeneous palladium catalyst can be recovered by simple filtration and reused several times without any decrease in activity.
Enantioselective Halo-oxy- and Halo-azacyclizations Induced by Chiral Amidophosphate Catalysts and Halo-Lewis Acids
Lu, Yanhui,Nakatsuji, Hidefumi,Okumura, Yukimasa,Yao, Lu,Ishihara, Kazuaki
supporting information, p. 6039 - 6043 (2018/05/14)
Catalytic enantioselective halocyclization of 2-alkenylphenols and enamides have been achieved through the use of chiral amidophosphate catalysts and halo-Lewis acids. Density functional theory calculations suggested that the Lewis basicity of the catalyst played an important role in the reactivity and enantioselectivity. The resulting chiral halogenated chromans can be transformed to α-Tocopherol, α-Tocotrienol, Daedalin A and Englitazone in short steps. Furthermore, a halogenated product with an unsaturated side chain may provide polycyclic adducts under radical cyclization conditions.
Synthesis of yomogin using a telescoped α-methylene-γ- butyrolactone annelation procedure
Kitson, Russell R.A.,McAllister, Graeme D.,Taylor, Richard J.K.
scheme or table, p. 561 - 564 (2011/03/18)
A novel and efficient synthetic route to the anti-cancer natural product yomogin has been developed using a Telescoped Intramolecular Michael-Olefination (TIMO) sequence as the key step. Two variants of the TIMO sequence have been used successfully: a two
Photo-induced intramolecular arene-olefin meta-cycloaddition of 5-phenyl-fluorinated-pent-1-enes
Guo, Xiao-Chuan,Chen, Qing-Yun
, p. 149 - 156 (2007/10/03)
A series of fluorinated angular and linear triquinanes and their aza-analogues have been synthesized by photo-induced intramolecular meta-cycloaddition of 5-phenyl-fluorinated-pent-1-enes.
