24363-87-9

Upstream product

• 934-32-7 1H-benzimidazol-2-amine 
• 2909-38-8 m-chlorophenyl isocyanate 
• 84388-88-5 2-Amino-benzoimidazole-1-carboxylic acid (3-chloro-phenyl)-amide 

Relevant academic research and scientific papers

Acylation of Heterocycles with Carbonic Acid Derivatives. II. Endo and Exo Carbamoylation of 2-Amino-benzimidazole Derivatives with Isocyanates. Mechanism of the Acyl Group Migration

2-Amino-benzimidazoles react with isocyanates with good yields to give 2-amino-1-carbamoyl-aminobenzimidazoles 1 at -30 deg C and the corresponding 2-carbamoyl isomeres 2 at room temperature, respectively.The isomerization mechanism was studied by crossov

N-heterocyclic ureas as immune regulants

Benzimidazolyl, benzothiazolyl and benzoxazolyl ureas and thioureas are employed as immune regulatory agents, as agents capable of altering the immune response in mammals.