24368-12-5Relevant academic research and scientific papers
Synthesis, spectral characterization and antimicrobial studies of transition metal complexes of benzothiazole based schiff bases
Das,Mohapatra,Patjoshi,El-Ajaily,Dash
, p. 2608 - 2614 (2018)
A series of transition metal complexes of the type [ML2]·nH2O, where L = 2-(benzothiazolyl-2'-Amino)iminoethanone (HBAE), 2-(benzothiazolyl-2'-Amino)imino-1,2-dimethylethanone (HBME), 2-(benzothiazolyl-2'-Amino)imino-1,2-diphenylethanone (HBPE), M = Cu(II), Co(II), Ni(II) and Zn(II), have been synthesized and characterized on the basis of spectral studies and thermal analyses. The spectroscopic data confirmed octahedral geometrical structures for all the complexes. All these Schiff bases and their metal complexes have been screened for their antibacterial activity against some pathogenic bacteria species (Bacillus subtilis, Bacillus stearothermophilus, Escherichia coli and Salmonella typhi) and antifungal activity against some pathogenic fungi strains (Aspergillus niger and Aspergillus flavus).
Synthesis, characterization, structure, DNA binding aspects and molecular docking study of a novel Schiff base ligand and its bis(μ-chloro) bridged Cu(II) dimer
Guhathakurta, Bhargab,Basu, Pritha,Purohit, Chandra Shekhar,Bandyopadhyay, Nirmalya,Kumar, Gopinatha Suresh,Chowdhury, Shubhamoy,Naskar, Jnan Prakash
, p. 195 - 204 (2017)
A novel Schiff base ligand, 2-(benzothiazol-2-yl-hydrazono)-1,2-diphenyl-ethanone (LH), has been synthesized out of the 1:1 condensation of benzil and 2-hydrazino benzothiazol in methanol. Reaction of equimolar proportion of LH and pre-activated CuCl2·2H2O in methanol generates bis(μ-chloro)bis(2-(benzothiazol-2-yl-hydrazono)-1,2-diphenyl-ethanoate)-dicopper(II), [Cu2(μ-Cl)2(L)2] (1) in copious yield. C, H and N microanalyses, ESI-MS, FT-IR, UV–Vis spectral studies have been undertaken to characterize LH and 1. The X-ray crystal structure of 1 has been determined. LH undergoes keto-enol tautomerism. The tautomeric aspects of LH have been corroborated through DFT calculations. LH binds to copper(II) in its enolate form to give rise the symmetric bis(μ-chloro) bridged copper(II) dimer. Both LH and 1 show the efficacy to bind CT DNA. The binding constants and the thermodynamic binding parameters have also been determined. A favourable major groove binding efficacy has been exposed for both the ligand and complex through molecular docking.
DNA and RNA binding studies on a novel bromo-bridged dimeric copper(II) complex stabilized from a Schiff base ligand
Mandal, Naba Kr,Guhathakurta, Bhargab,Basu, Pritha,Pradhan, Ankur Bikash,Purohit, Chandra Shekhar,Chowdhury, Shubhamoy,Naskar, Jnan Prakash
, p. 3625 - 3644 (2019)
A novel red copper(II) compound, bis(μ-bromo)bis(2-(benzothiazol-2-yl-hydrazono)-1,2-diphenyl-ethanone)-dicopper(II) (1), has been fostered by equimolar reaction of a Schiff-base ligand, 2-(benzothiazol-2-yl-hydrazono)-1,2-diphenyl-ethanone (LH), with cop
Synthesis and characterization of uranyl [UO22+] complexes with benzothiazolyl hydrazones of benzil and diacetyl
Dash,Mahapatra,Mishra,Mishra,Naik
, p. 1263 - 1266 (2008/09/20)
A few uranyl complexes of the type [UO2L(H2O) 2NO3] and [UO2L2(H 2O)2]; where HL is a Schiff base obtained by the condensation of 2-hydrazinobenzothiazole with benzil and diacetyl such as 2-(benzothiazolyl-2′-amino)imino1,2-diphenylethanone (HBTDPE) and 2-(benzothiazolyl-2′-amino)imino-1,2-dimethylethanone (HBTDME) have been synthesized and characterized on the basis of elemental analysis, molar conductance, thermal analysis, infrared, electronic spectra and 1H NMR studies. The results indicate that the former series of complexes of [UO22+] are six coordinated, while the later series of complexes are eight coordinated.
