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N-[4-(4-Fluoro-phenyl)-thiazol-2-yl]-guanidine is a chemical compound with the molecular formula C10H9FN4S. It features a guanidine group attached to a thiazol-2-yl ring, which is further connected to a 4-fluoro-phenyl group. N-[4-(4-FLUORO-PHENYL)-THIAZOL-2-YL]-GUANIDINE is known for its potential applications in pharmaceutical research, particularly as a building block for the development of new drugs. Its structure allows for the exploration of various biological activities, making it a valuable tool in the synthesis of therapeutic agents. The presence of the fluorine atom can influence the compound's lipophilicity and metabolic stability, which are important factors in drug design.

2438-34-8

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2438-34-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2438-34-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,4,3 and 8 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 2438-34:
(6*2)+(5*4)+(4*3)+(3*8)+(2*3)+(1*4)=78
78 % 10 = 8
So 2438-34-8 is a valid CAS Registry Number.

2438-34-8Downstream Products

2438-34-8Relevant academic research and scientific papers

Method for synthesizing 2-guanidinothiazole compound by one-pot process

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Paragraph 0014, (2020/11/09)

According to the invention, a substituted methyl ketone compound is innovatively used as a raw material, amidinothiourea is added into an alcohol solvent under the conditions of halogeno salt MX and Oxone, and a one-pot process one-step reaction is carried out to obtain the target 2-guanidinothiazole compound. Common methyl ketone is used for replacing an alpha-halogenated carbonyl compound whichis high in price and toxicity, MX which is low in price and easy to obtain is used as a halogen source, the method is novel, raw materials and reagents are cheap, reaction conditions are mild, and operation is easy and convenient, therefore low-cost, convenient and rapid synthesis of the 2-guanidinothiazole compound is achieved.

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