2439-07-8

Basic information

• Product Name: salicylic acid, compound with quinolin-8-ol (1:1)
• Synonyms: 8-Quinolinol, salicylate (salt); 8-Hydroxyquinoline salicylate; Benzoic acid, 2-hydroxy-, compd. with 8-quinolinol (1:1); NSC 3907; Salicylate of 8-oxyquinoline; Benzoic acid, 2-hydroxy-, compd. with 8-quinolinol (1:1) (9CI); Salicylic acid, compound with quinolin-8-ol (1:1); 2-hydroxybenzoic acid - quinolin-8-ol (1:1)
• CAS NO: 2439-07-8
• Molecular Formula: C₇H₆O₃*C₉H₇NO
• Molecular Weight: 283.2787
• EINECS: 219-457-4
• Mol File: 2439-07-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 267°C at 760 mmHg
• Flash Point: 143.1°C
• Vapor Pressure: 0.00508mmHg at 25°C
• CAS DataBase Reference: salicylic acid, compound with quinolin-8-ol (1:1)(CAS DataBase Reference)
• NIST Chemistry Reference: salicylic acid, compound with quinolin-8-ol (1:1)(2439-07-8)
• EPA Substance Registry System: salicylic acid, compound with quinolin-8-ol (1:1)(2439-07-8)

Safety Data

• Hazardous Substances Data: 2439-07-8(Hazardous Substances Data)

Usage

General Description

Salicylic acid, compound with quinolin-8-ol (1:1) is a chemical combination of salicylic acid and quinolin-8-ol in a 1:1 ratio. Salicylic acid is a beta hydroxy acid with exfoliating properties that helps to unclog pores and reduce inflammation, making it a popular ingredient in skincare products for treating acne and exfoliating the skin. Quinolin-8-ol, also known as oxine, is a heterocyclic compound with antifungal and antimicrobial properties. When combined with salicylic acid, it may enhance the antimicrobial and exfoliating effects of the individual compounds, making it a potentially effective ingredient in skincare products for acne and other skin conditions.

Upstream product

• 148-24-3 8-quinolinol 
• 69-72-7 salicylic acid 

Relevant articles and documents

Reaction between 8-hydroxyquinoline and salicylic acid in solid state and solution

8-Hydroxyquinoline reacts with salicylic acid both in solid state and solution forming a yellow coloured compound. Phase diagram studies have shown the formation of a 1:1 addition compound stable in solid state and dissociated in solution. Differential thermal studies have shown that the reaction products obtained from solution and solid state reaction are almost identical except that there is a possibility of entrapped solvent molecules when the product was prepared from benzene. Also the reaction product shows a thermochromic effect. X-ray diffraction studies have revealed some structural difference between the reaction product obtained from solution and solid state reaction. Spectroscopic studies show the possibility of hydrogen bonding in the reaction product. The reaction in the solid state is slow and once a thin layer of reaction product is formed at the surface of salicylic acid crystals, the reaction rate becomes practically negligible. This may be due to the compactness of the product layer and unfavourable crystal packing in to the crystal lattice of salicylic acid. Microstructural studies have shown that there are structural changes during solid state reaction. by Oldenbourg Wissenschaftsverlag, Muenchen.