243977-15-3 Usage
Uses
4-Amino-8-(trifluoromethyl)quinoline is used to synthesis of rubber chemical, antiseptic, antipyretic, and antiperiodic properties and are used as antimalarials and for preparing other antimalarial drugs
Check Digit Verification of cas no
The CAS Registry Mumber 243977-15-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,4,3,9,7 and 7 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 243977-15:
(8*2)+(7*4)+(6*3)+(5*9)+(4*7)+(3*7)+(2*1)+(1*5)=163
163 % 10 = 3
So 243977-15-3 is a valid CAS Registry Number.
InChI:InChI=1/C10H7F3N2/c11-10(12,13)7-3-1-2-6-8(14)4-5-15-9(6)7/h1-5H,(H2,14,15)
243977-15-3Relevant articles and documents
In situ generation of ammonia for the copper-catalyzed synthesis of primary aminoquinolines
Aillerie, Alexandre,Pellegrini, Sylvain,Bousquet, Till,Pélinski, Lydie
, p. 1389 - 1391 (2014/05/06)
The synthesis of primary aminoquinolines from iodoquinolines was carried out in the presence of copper(i) iodide and formamide as the solvent and source of ammonia generated in situ. The reaction proceeded under mild conditions within a few hours and was applicable to various iodoquinolines.