243978-85-0Relevant articles and documents
Synthesis and glycosidase inhibitory activity of aminocyclitols with a C6- or a C7-ring
Gravier-Pelletier, Christine,Maton, William,Dintinger, Thierry,Tellier, Charles,Le Merrer, Yves
, p. 8705 - 8720 (2007/10/03)
The synthesis of carbasugars and various aminocyclitols, related to voglibose and acarbose used in the treatment of non-insulino-dependant diabetes, is described from C2-symmetrical bis-epoxides derived from D-mannitol. The methodology involves
A Concise Route to Carbasugars
Merrer, Yves Le,Gravier-Pelletier, Christine,Maton, William,Numa, Mehdi,Depezay, Jean-Claude
, p. 1322 - 1324 (2007/10/03)
An efficient method for the synthesis of enantiopure carbasugars with a C6- or symmetrical C7-ring has been developed from C2-symmetric bis-epoxides issued from D-mannitol. The methodology involves a tandem alkylation-cyclization with 2-lithio-