243988-34-3Relevant academic research and scientific papers
Synthesis of dihydropyrroles by the intramolecular addition of alkylideneaminyl radicals generated from O-2,4-dinitrophenyloximes of γ,δ- unsaturated ketones
Uchiyama, Katsuya,Hayashi, Yujiro,Narasaka, Koichi
, p. 8915 - 8930 (1999)
Alkylideneaminyl radicals are generated from O-2,4-dinitrophenyloximes of γ,δ-unsaturated ketones by treatment with NaH and 3,4- methylenedioxyphenol. The resulting radical species successively add to the olefinic moiety intramolecularly to afford dihydropyrroles in the presence of a radical trapping agent. This method is applied for the stereoselective synthesis of xenovenine, a bicyclic 3,5-dialkylpyrrolizidine alkaloid.
