244056-65-3

Upstream product

• 93-56-1 phenylethane 1,2-diol 
• 181790-68-1 (2S,2S')-2,2'-Bis(triisopropylsilyloxymethyl)-3,3',4,4'-tetrahydro-6,6'-bi-2H-pyran 
• 13154-24-0 triisopropylsilyl chloride 
• 244056-57-3 (2R,6R,7S,9R,14S)-14-Phenyl-2,9-bis(triisopropylsilyloxymethyl)-1,8,13,16-tetraoxadispiro<5.0.5.4>hexadecane 
• 1026520-78-4 (2R,6S,7S,9R,14S)-14-Phenyl-1,8,13,16-tetraoxa-dispiro[5.0.5.4]hexadecane-2,9-dicarbaldehyde 
• 244056-49-3 (S)-6-Hydroxy-7-triisopropylsilyloxyhept-1-ene 
• 244056-51-7 (S)-6-Hydroxy-2-triisopropylsilyloxymethyl-3,4,5,6-tetrahydro-2H-pyran 
• 181790-66-9 1,5-anhydro-1,2,3,4-tetradeoxy-6-O-(triisopropylsilyl)-D-glycero-hex-1-enitol 
• 185140-87-8 (2S)-2,3-Epoxy-1-(triisopropylsilyloxy)propane 
• 244056-58-4 (2R,6R,7S,9R,14S)-2,9-Bis(hydroxymethyl)-14-phenyl-1,8,13,16-tetraoxadispiro<5.0.5.4>hexadecane 

Downstream Products

• 16355-00-3 (R)-1-phenyl-1,2-ethanediol 
• 78692-90-7 (R)-2-methylcarbonyloxy-1-phenylethyl acetate 
• 244056-66-4 (2S,6S,7R,9S,14R)-2,9-Bis(hydroxymethyl)-14-phenyl-1,8,13,16-tetraoxadispiro<5.0.5.4>hexadecane 

Relevant academic research and scientific papers

Dispiroketals in synthesis. Part 24. Preparation and use of chiral 2,2′-bis(triisopropylsilyloxymethyl)bi(dihydropyran)s as new protecting and resolving agents for 1,2-diols

C2 symmetric chiral 2,2′-bis(triisopropylsilyloxymethyl)bi(dihydropyran)s (S,S)-1 and (R,R)-1 were prepared from the corresponding glycidols and selectively reacted with 1,2-diols to give dispiroketals. The products of these reactions could be deprotected following treatment with fluoride, oxidation and reductive cleavage with samarium(II) iodide.