244081-45-6Relevant articles and documents
-Catalyzed cascade arylation and chlorination of α-diazocarbonyl compounds with arylboronic acids and n -chlorosuccinimide for facile synthesis of α-aryl-α-chloro carbonyl compounds
Ng, Fo-Ning,Lau, Yan-Fung,Zhou, Zhongyuan,Yu, Wing-Yiu
, p. 1676 - 1679 (2015)
A Rh(III)-catalyzed cascade arylation and chlorination of α-diazocarbonyl compounds with arylboronic acids and N-chlorosuccinimide was achieved. The reaction exhibits excellent functional group tolerance on the organoboron and the diazo reagents; the functionalized α-aryl-α-chlorocarbonyl compounds were obtained in up to 86% yields. The cascade reaction should involve migratory carbene insertion of arylrhodium(III) to form some reactive rhodium(III)-diketonate complexes. Its subsequent reaction with N-chlorosuccinmide afforded the α-chlorocarbonyl products.
