244094-95-9Relevant academic research and scientific papers
Dibutyl tin oxide mediated, regioselective alkylation and acylation of siloxane protected glycopyranosides
Ziegler, Thomas,Dettmann, Ralf,Grabowski, Jaroslaw
, p. 1661 - 1665 (1999)
Treatment of alkyl and aryl 4,6-O-(1,1,3,3-tetraisopropyl-1,3- disiloxane-1,3-diyl)-D-glycopyranosides 2 with dibutyltin oxide followed by benzoyl chloride, benzyl bromide and allyl bromide afforded regioselectively the corresponding mono acylated and alkylated glycosides. The regioselective acylation of the stannylene intermediates is inverted as compared to the direct acylation of 2. Regioselective alkylations of 2 proceeded without affecting the siloxane residue.
