24410-58-0 Usage
Uses
Used in Research Applications:
4-Fluorobenzofuran is utilized as a research chemical for the investigation of its psychoactive properties and potential effects on the serotonin system. It aids scientists in understanding the mechanisms of action and potential applications in the field of psychopharmacology.
Used in Pharmaceutical Development:
Although not approved for medical use, 4-Fluorobenzofuran may serve as a lead compound in the development of new pharmaceuticals targeting the serotonin system for the treatment of various disorders. Its potential as a serotonin releasing agent could be harnessed in the creation of novel therapeutic agents.
Used in Forensic Toxicology:
4-Fluorobenzofuran's classification as a designer drug and psychoactive substance makes it relevant in forensic toxicology for the identification and analysis of substances in cases involving drug abuse or intoxication.
Check Digit Verification of cas no
The CAS Registry Mumber 24410-58-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,4,4,1 and 0 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 24410-58:
(7*2)+(6*4)+(5*4)+(4*1)+(3*0)+(2*5)+(1*8)=80
80 % 10 = 0
So 24410-58-0 is a valid CAS Registry Number.
24410-58-0Relevant academic research and scientific papers
Synthesis and structure-activity relationship of dihydrobenzofuran derivatives as novel human GPR119 agonists
Ye, Xiang-Yang,Morales, Christian L.,Wang, Ying,Rossi, Karen A.,Malmstrom, Sarah E.,Abousleiman, Mojgan,Sereda, Larisa,Apedo, Atsu,Robl, Jeffrey A.,Miller, Keith J.,Krupinski, John,Wacker, Dean A.
, p. 2539 - 2545 (2014/05/20)
Through appropriate medicinal chemistry design tactics and computer-assisted conformational modeling, the initial lead A was evolved into a series of dihydrobenzofuran derivatives 3 as potent GPR119 agonists. This Letter describes the optimization of general structure 3, including the substituent(s) on dihydrobenzofuran, the R1 attachment on right-hand piperidine nitrogen, and the left-hand piperidine/piperazine and its attachment R2. The efforts led to the identification of compounds 13c and 24 as potent human GPR119 modulators with favorable metabolic stability, ion channel activity, and PXR profiles.
