244135-36-2Relevant academic research and scientific papers
Synthesis and preliminary pharmacological evaluation of thiophene analogues of viloxazine as potentialantidepressant drugs
Corral, Carlos,Lissavetzky, Jaime,Manzanares, Ignacio,Darias, Victoriano,Exposito-Orta, Maria A.,Martin Conde, Jose A.,Sanchez-Mateo, C.Carmen
, p. 1349 - 1359 (2007/10/03)
A series of eight thienyloxymethylmorpholines, thiophene analogues of viloxazine, have been synthesized by three different routes. The preliminary pharmacological evaluation of this series shows antidepressant properties on the mice models used with a light sedative action. The structure-activity relationship is established in a first approximation. Copyright (C) 1999 Elsevier Science Ltd.
