244138-37-2Relevant academic research and scientific papers
Generation of acetylides by treatment of fluoroethylenes with LDA: Preparation of propargyl alcohols
Kataoka, Kentaro,Tsuboi, Sadao
, p. 452 - 456 (2000)
The fluoroethylenes 3 produced the corresponding acetylides via dehydrofluorination and deprotonation by treatment with 2 equivalents of LDA in THF at 0 °C. These acetylides reacted with aldehydes and ketones to afford propargyl alcohols in good yields.
Synthesis of monofluoroalkenes via Julia-Kocienski reaction
Prakash, G.K. Surya,Shakhmin, Anton,Zibinsky, Mikhail,Ledneczki, Istvan,Chacko, Sujith,Olah, George A.
experimental part, p. 1192 - 1197 (2011/02/22)
Monofluoromethyl 3,5-bis(trifluoromethyl)phenyl sulfone 1 was synthesized and employed in Julia-Kocienski fluoroolefination reaction with various ketones and aldehydes. Optimal reaction conditions were found to be the treatment of substrates with KOH or C
