244151-81-3Relevant academic research and scientific papers
Pyrrolobenzimidazoles Linked to Heterocycles and Peptides. Design of DNA Base Pair Specific Phosphate Hydrolyzing Agents and Novel Cytotoxic Agents
Ghodousi, Arman,Huang, Xiaofen,Cheng, Zheng,Skibo, Edward B.
, p. 90 - 100 (2007/10/03)
Work in this laboratory has been involved with the design of aziridinyl quinone-based cancer drugs (PBIs) capable of both recognizing the DNA major groove and cleaving the phosphate backbone upon reduction to the hydroquinone. The hydroquinone species rec
