244176-55-4Relevant academic research and scientific papers
General 5-Halomethyl Isoxazoline Synthesis Enabled by Copper-Catalyzed Oxyhalogenation of Alkenes
Li, Xiaoqing,Ding, Yu,Qian, Lijie,Gao, Yang,Wang, Xinqiang,Yan, Xinhuan,Xu, Xiangsheng
, p. 12656 - 12663 (2019/10/14)
A general and efficient oxyhalogenation of unsaturated ketoximes has been achieved through copper catalysis with diethyl bromomalonate, N-chlorosuccinimide, and N-iodosuccinimide, yielding 5-chloromethyl, 5-bromomethyl, and 5-iodomethyl isoxazolines in go
5-Bromomethyl-4,5-dihydroisoxazoles
Mosher, Michael D.,Norman, Amber L.,Shurrush, Khriesto A.
supporting information; scheme or table, p. 5647 - 5648 (2011/02/25)
The preparation of substituted 4,5-dihydroisoxazoles can be accomplished via the treatment of β,γ-unsaturated oximes with liquid bromine. The reaction provides a convenient route to the highly functionalized title compounds.
Ring opening of 5-(bromomethyl)-2-isoxazolines with magnesium metal in absolute MeOH
Ha, Sung Jin,Lee, Ge Hyeong,Yoon, In Kwon,Pak, Chwang Siek
, p. 3165 - 3177 (2007/10/03)
Ring opening of 5-(bromomethyl)- and 5-(phenylsulfonylmethyl)-2- isoxazolines with magnesium in absolute methanol at -23 °C and room temperature afforded regiospecifically β,γ-enoximes and (E)-α,β-enoximes, respectively.
