2442-81-1

Basic information

• Product Name: 1,4-Benzenediamine,N-ethyl-N-methyl-(9CI)
• Synonyms: 1,4-Benzenediamine,N-ethyl-N-methyl-(9CI);N-Ethyl-N-methyl-benzene-1,4-diamine;N1-Ethyl-N1-methylbenzene-1,4-diamine;N1-Ethyl-N1-methyl-1,4-benzenediamine 2HCl
• CAS NO: 2442-81-1
• Molecular Formula: C₉H₁₄N₂
• Molecular Weight: 150.224
• Product Categories: AMINEPRIMARY
• Mol File: 2442-81-1.mol

Chemical Properties

• Boiling Point: 280.1 °C at 760 mmHg
• Flash Point: 142.8 °C
• Appearance: /
• Density: 0.988 g/cm³
• PKA: 7.49±0.32(Predicted)
• Water Solubility: at 25 deg C (mg/L): 4900
• CAS DataBase Reference: 1,4-Benzenediamine,N-ethyl-N-methyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Benzenediamine,N-ethyl-N-methyl-(9CI)(2442-81-1)
• EPA Substance Registry System: 1,4-Benzenediamine,N-ethyl-N-methyl-(9CI)(2442-81-1)

Safety Data

• Hazardous Substances Data: 2442-81-1(Hazardous Substances Data)

Usage

Uses

Used in Chemical Industry:
1,4-Benzenediamine, N-ethyl-N-methyl-(9CI) is used as a key component in the synthesis of dyes and pigments for various applications, such as coloring textiles, plastics, and other materials.
Used in Cosmetics Industry:
In the cosmetics industry, 1,4-Benzenediamine, N-ethyl-N-methyl-(9CI) is utilized as an ingredient in hair dyes, providing color to hair while posing potential health risks due to its irritant and carcinogenic nature.
Used in Rubber Industry:
1,4-Benzenediamine, N-ethyl-N-methyl-(9CI) is also employed in the production of certain types of rubber, contributing to the development of rubber products with specific properties.
Due to the hazardous nature of 1,4-Benzenediamine, N-ethyl-N-methyl-(9CI), it is regulated in many countries, and its handling requires caution to minimize exposure and potential health risks.

Upstream product

• 36479-98-8 N-ethyl-N-methyl-4-nitrosoaniline 

Downstream Products

• 100517-64-4 [4-(ethyl-methyl-amino)-phenylimino]-malononitrile 
• 1111628-59-1 1-[2,3-di(tert-butoxycarbonyl)guanidino]-4-(N-ethyl-N-methyl)benzene 
• 1111628-54-6 2-(4-(ethylmethylamino)phenylimino)-imidazolidine-1,3-dicarboxylic acid di-tert-butyl ester 
• 1255709-26-2 2-amino-5-ethylmethylaminophenyl thiosulfonic acid 
• 36460-76-1 C₁₃H₂₁N₃ 
• 101288-47-5 benzoic acid-[4-(ethyl-methyl-amino)-anilide] 

Relevant articles and documents

a2-Adrenoceptor Ligands

The adrenergic receptors or adrenoceptors are a family of G-protein coupled receptors split into α and β subclasses. The adrenoceptors have important roles in regulating a myriad of physiological conditions and their malfunction has been implicated in the pathophysiology of a number of diseases. Disclosed herein are a series of novel compounds which are ligands of the alpha2-adrenoceptor (α2-ARs) subclass of adrenergic receptors. The invention also provides for pharmaceutical compositions comprising the novel compounds. The compounds are suitable for use in the manufacture of medicaments for the treatment of α2-ARs associated disorders, such as depression and schizophrenia.

Guanidine and 2-aminoimidazoline aromatic derivatives as α2-adrenoceptor ligands: Searching for structure-activity relationships

In this paper, we report the synthesis of three new 2-aminoimidazoline (compounds 4b, 5b, and 6b) and three new guanidine derivatives (compounds 7b, 8b, and 9b) as potential α2-adrenoceptor antagonists for the treatment of depression. Their pha