244236-48-4

Upstream product

• 1026213-65-9 4,6-dichloro-3-phenylcarbamoylethynyl-1-(2-trimethylsilanyl-ethoxymethyl)-1H-indole-2-carboxylic acid 
• 153435-98-4 4,6-dichloro-3-(2,2-dibromovinyl)-1-(2-trimethylsilanylethoxymethyl)-indole-2-carboxylic acid ethyl ester 
• 153435-99-5 3-bromoethynyl-4,6-dichloro-1-(2-trimethylsilanylethoxymethyl)-indole-2-carboxylic acid ethyl ester 
• 153436-00-1 3-bromoethynyl-4,6-dichloro-1-(2-trimethylsilanylethoxymethyl)-indole-2-carboxylic acid 
• 153435-97-3 4,6-dichloro-3-formyl-1-(2-trimethylsilanylethoxymethyl)-indole-2-carboxylic acid ethyl ester 
• 153435-96-2 ethyl-3-formyl-4,6-dichloro-indole-2-carboxylate 
• 153436-01-2 4,6-dichloro-3-[(2-phenylcarbamoyl)-ethynyl]-1-(2-trimethylsilanylethoxymethyl)-indole-2-carboxylic acid methyl ester 

Downstream Products

• 153436-31-8 4,6-dichloro-3-phenylcarbamoylethynyl-indole-2-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Synthesis of substituted indole-2-carboxylates: Versatile introduction of a carbamoyl moiety at the C-3 position

This paper deals with a novel and versatile synthetic approach for the introduction of a functionalized ethynyl side chain at the C-3 position of the 2-carboxyindole nucleus. The key step of this process is represented by the coupling reaction between the