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• 98-59-9 p-toluenesulfonyl chloride 
• 102-50-1 2-methyl-4-methoxyaniline 

Relevant academic research and scientific papers

Highly chemo- and regioselective C-P cross-coupling reaction of quinone imine ketals with Ar2P(O)H to construct: Ortho -amino triarylphosphine derivatives

A highly chemo- and regioselective approach for the construction of ortho-amino triarylphosphine oxides has been achieved through a C-P cross-coupling reaction involving quinone imine ketals (QIKs) with Ar2P(O)H and catalyzed via a Lewis base. This alternative protocol provided a wide substrate scope with excellent yields (82-95%), and a variety of ortho-amino triarylphosphines were obtained with high yields (87-95%) via further reductive reaction. Furthermore, this reaction could be scaled-up and several synthetic transformations were accomplished for the construction of functionalized organophosphorus.

A chemical synthesis asymmetric structure dihalodiarylsulfone method (by machine translation)

A chemical synthesis asymmetric structure dihalodiarylsulfone method, to substituted aniline compound 1 as a starting raw material, first on the aniline Ts (toluene sulfonyl) protection or Boc (tert-butoxy carbonyl) protection of the compound 2 or 4. Under the room temperature condition, compound 2 or 4 is dissolved in methanol or ethanol or isopropanol, then under the protection of nitrogen [...] diacetic acid [PhI (OAc)2 ] Oxidation to obtain compound 3 or 5. In the three ethylene diamine (DABCO) as catalyst and polyethylene glycol (PEG - 400) as reaction solvent 40 o C conditions, compound 5 with compound 6 in 1, 4 - conjugate addition reaction/sulfonylimines acylation reaction asymmetric structure dihalodiarylsulfone 7. The raw material is cheap and easy to obtain, reaction selectivity, and reaction solvent polyethylene glycol (PEG - 400) can be recycled 4 - 5 times less environmental pollution, high yield and easy application and the like. (by machine translation)