24431-49-0

Basic information

• Product Name: 3-(1,3-dioxoisoindolin-2-yl)-2-methylpropanoic acid
• Synonyms: 3-(1,3-dioxoisoindolin-2-yl)-2-methylpropanoic acid
• CAS NO: 24431-49-0
• Molecular Weight: 233.224
• Mol File: 24431-49-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3-(1,3-dioxoisoindolin-2-yl)-2-methylpropanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(1,3-dioxoisoindolin-2-yl)-2-methylpropanoic acid(24431-49-0)
• EPA Substance Registry System: 3-(1,3-dioxoisoindolin-2-yl)-2-methylpropanoic acid(24431-49-0)

Safety Data

• Hazardous Substances Data: 24431-49-0(Hazardous Substances Data)

Upstream product

• 5428-09-1 3-phthalimido-1-propene 
• 85-44-9 phthalic anhydride 
• 10569-72-9 DL-3-aminoisobutyric acid 

Downstream Products

• 1174762-96-9 2-methyl-3-(1,3-dioxoisoindolin-2-yl)-N-(perfluorophenyl)propanamide 
• 1214742-45-6 C₃₃H₄₅N₃O₅ 

Relevant articles and documents

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Carbonylative Transformation of Allylarenes with CO Surrogates: Tunable Synthesis of 4-Arylbutanoic Acids, 2-Arylbutanoic Acids, and 4-Arylbutanals

In this Communication, procedures for the selective synthesis of 4-arylbutanoic acids, 2-arylbutanoic acids, and 4-arylbutanals from the same allylbenzenes have been developed. With formic acid or TFBen as the CO surrogate, reactions proceed selectively and effectively under carbon monoxide gas-free conditions.

Pd(II)-catalyzed C(sp3)-H arylation of amino acid derivatives with click-triazoles as removable directing groups

By using click-triazoles as conveniently approachable and removable directing groups, the direct palladium-catalyzed C(sp3)-H arylation of amino acid derivatives with various aryl iodides bearing different electronic properties has been achieved. Notably, the desired amino acid molecule can be obtained by the cleavage of the tethered click-triazoles after the catalytic reaction, which aims to provide a practical protocol for the accessibility of both natural and synthetic amino acids.