2445-91-2Relevant articles and documents
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Kim,Cocolas
, p. 83 (1967)
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2-PYRROLIDONE SUBSTITUTED DIHYDROXY ALKANOIC, ALKENOIC AND ALKYNOIC ACIDS, COMPOSITIONS AND HMG-COA REDUCTASE INHIBITION THEREWITH
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, (2008/06/13)
Antihypercholesterolemic activity has been discovered in compounds of the formula and pharmaceutically acceptable salts thereof, wherein: Z is X is lower alkyl, lower alkenyl, or lower alkenyl; R1 is hydrogen, alkyl, alkenyl, aryl, alkylaryl, or substituted aryl having one or more substituents; and one of R2 and R3 is hydrogen and the other is hydrogen, alkyl, alkenyl, aryl, alkylaryl or alkenyl aryl; or R2 and R3 are both lower alkyl; or R2 and R3 together complete a substituted or unsubstituted hydrocarbon ring that is cycloalkyl or cycloalkenyl with substituents as defined in the specification.