2445-97-8 Usage
Uses
Used in Pharmaceutical Industry:
(2S,3R)-3-METHYLGLUTAMIC ACID HYDROCHLORIDE SALT is used as a pharmaceutical agent for its role in modulating neurotransmission. Its agonist activity on kainate receptors makes it a potential candidate for the development of drugs targeting neurological disorders and conditions related to glutamate signaling.
Used in Research and Development:
(2S,3R)-3-METHYLGLUTAMIC ACID HYDROCHLORIDE SALT is used as a research tool for studying the function and regulation of kainate receptors, as well as the broader glutamate signaling pathway. This can contribute to a better understanding of the underlying mechanisms of various neurological conditions and the development of novel therapeutic strategies.
Used in Neurochemistry:
(2S,3R)-3-METHYLGLUTAMIC ACID HYDROCHLORIDE SALT is used as a neurochemical agent to investigate the role of glutamate transport in the central nervous system. Its inhibitory effect on glutamate transport can provide insights into the regulation of glutamate homeostasis and its implications in neurological health and disease.
Check Digit Verification of cas no
The CAS Registry Mumber 2445-97-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,4,4 and 5 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 2445-97:
(6*2)+(5*4)+(4*4)+(3*5)+(2*9)+(1*7)=88
88 % 10 = 8
So 2445-97-8 is a valid CAS Registry Number.
InChI:InChI=1/C6H11NO4.ClH/c1-3(2-4(8)9)5(7)6(10)11;/h3,5H,2,7H2,1H3,(H,8,9)(H,10,11);1H/t3-,5+;/m0./s1
2445-97-8Relevant academic research and scientific papers
threo-Selective Michael Addition of N,N-Dibenzylglycinate and Alaninate Enolates to α,β-Unsaturated Esters. A Concise and Stereoselective Synthesis of (+/-)-CCG-II
Yamaguchi, Masahiko,Torisu, Kazuhiko,Minami, Toru
, p. 377 - 380 (2007/10/02)
Lithium enolates of N,N-dibenzylglycinate and alaninate added to β-substituted α,β-unsaturated esters, and threo-adducts were obtained in high stereoselectivities.The reaction was employed in a concise and stereoselective synthesis of (+/-)-CCG-II.
SYNTHESIS OF ω-HYDROXY ANALOGUES OF VALINE, LEUCINE AND ISOLEUCINE
Englisch-Peters, Sabine
, p. 6127 - 6134 (2007/10/02)
The isomers of γ-hydroxy-valine (6) were prepared by a modified Erlenmeyer synthesis and the δ-hydroxy analogues each of leucine (16a) and isoleucine (16b) were synthesized via 1,4-Michael addition.The diastereomers of 6 could be separated by column chrom
