244614-13-9

Upstream product

• 71735-01-8 (E)-3-(tert-butyldimethylsilyloxy)-1-methoxy-1,3-butadiene 
• 104-88-1 4-chlorobenzaldehyde 
• 194233-66-4 (1E)-3-{[tert-butyl(dimethyl)silyl]oxy}-N,N-dimethyl-1,3-butadien-1-amine 
• 88146-60-5 1-tert-Butoxy-3-<(trimethylsilyl)oxy>butadiene 
• 54125-02-9 danishefsky's diene 

Relevant academic research and scientific papers

Enantiopure (P)- and (M)-3,14-bis(o-hydroxyaryl)tetrahydrobenzo[5]helicenediols and their helicene analogues: Synthesis, amplified circularly polarized luminescence and catalytic activity in asymmetric hetero-Diels–Alder reactions

Three pairs of enantiopure (P)- and (M)-3,14-bis(o-hydroxyaryl)tetrahydrobenzo[5]helicenediols (ArOH-H[5]HOLs), and enantiomers (P)- and (M)-3,14-bis(o-hydroxyphenyl)benzo[5]helicene-diols (PhOH-[5]HOLs) were designed and synthesized. It was found that co

Silica-based helical rod supporting guanosine compounds catalyzed asymmetric hetero-Diels-Alder reaction

A series of silica-based helical rods were prepared and functionalized for immobilization of guanosine compounds in catalytic asymmetric hetero-Diels-Alder reaction. Nitrogen physisorption, electron microscopy and amino acid adsorption revealed that helic

cis-2,5-diaminobicyclo[2.2.2]octane, a new scaffold for asymmetric catalysis via salen-metal complexes

Chemical equations presented. A new C2 symmetric salen scaffold based on cis-2,5-diaminobicyclo[2.2.2]octane has been synthesized that forms complexes with a wide range of metals. The chromium(III) complex is shown to catalyze the hetero-Diels-

Oxo-Diels-Alder reaction of danishefskys diene with aldehydes, catalyzed by chiral tridentate chromium(III)-Schiff base complexes

The enantioselective hetero-Diels-Alder reaction of Danishefskys diene with simple aromatic and aliphatic aldehydes is catalyzed by chiral tridentate Schiff base-chromium(III) complexes. In many cases, 2,3-dihydropyran-4-ones are obtained in good yields (

Evaluation of catalyst acidity and substrate electronic effects in a hydrogen bond-catalyzed enantioselective reaction

A modular catalyst structure was applied to evaluate the effects of catalyst acidity in a hydrogen bond-catalyzed hetero Diels-Alder reaction. Linear free energy relationships between catalyst acidity and both rate and enantioselectivity were observed, wh

A novel chiral H′4-NOBIN schiff base for hetero-diels-alder reaction of danishefsky's diene with aldehydes

Novel chiral H′4-NOBIN was synthesized in 66% yield through partial hydrogenation of 2-amino-2′-hydroxy-1,1′-binaphthyl, and the structure was proved via X-ray analysis of its salicylaldehyde Schiff base, which was tested in the enantioselectiv

Methods of performing cycloadditions, reaction mixtures, and methods of performing asymmetric catalytic reactions

Methods of performing cycloadditions are described that include (a) combining a first reactant and a second reactant in a hydrogen bonding solvent to form a reaction mixture; and (b) reacting the first reactant and the second reactant to form a cycloadduc

Storable, powdered chiral zirconium complex for asymmetric aldol and hetero Diels-Alder reactions

A storable, powdered chiral zirconium catalyst for asymmetric aldol and hetero Diels-Alder reactions has been developed. The catalyst has the same activity as that prepared in situ even after being stored for 3 months. Moreover, this chiral Zr catalyst wo

A new dirhodium(II) carboxamidate complex as a chiral Lewis acid catalyst for enantioselective hetero-Diels-Alder reactions

Excellent enantioselectivities (up to 99% ee) and turnover numbers (up to 48000) were attained in the hetero-Diels-Alder reaction of a diverse range of aldehydes and activated dienes catalyzed by [Rh2(S-bptpi) 4] (see scheme).

Chiral rare earth organophosphates as homogeneous Lewis acid catalysts for the highly enantioselective hetero-Diels-Alder reactions

Various trivalent rare earth-chiral phosphate complexes [(R)-1-RE, (R)-3-RE, and (R)-4-Ce] were prepared and evaluated as a Lewis acid catalyst for the asymmetric hetero-Diels-Alder reaction of aldehydes with the Danishefsky's diene. Some of them effectiv