24463-56-7

Basic information

• Product Name: 4H-1,2,4-Triazole, 4-(1-methylethyl)-
• Synonyms: 4H-1,2,4-Triazole,4-(1-methylethyl);4-isopropyl-1,2,4-triazole
• CAS NO: 24463-56-7
• Molecular Formula: C5H9N3
• Molecular Weight: 111.147
• Mol File: 24463-56-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 194.3±23.0 °C(Predicted)
• Density: 1.08±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 4H-1,2,4-Triazole, 4-(1-methylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-1,2,4-Triazole, 4-(1-methylethyl)-(24463-56-7)
• EPA Substance Registry System: 4H-1,2,4-Triazole, 4-(1-methylethyl)-(24463-56-7)

Safety Data

• Hazardous Substances Data: 24463-56-7(Hazardous Substances Data)

Upstream product

• 288-88-0 1,2,4-Triazole 
• 75-30-9 2-iodo-propane 

Downstream Products

• 1448427-99-3 6-[4-(propan-2-yl)-4H-1,2,4-triazol-3-yl]pyridin-2-amine 
• 1448428-04-3 5-(4-cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methyl-N-{6-[4-(propan-2-yl)-4H-1,2,4-triazol-3-yl]pyridin-2-yl}benzamide 

Relevant articles and documents

An investigation into the alkylation of 1,2,4-triazole

The alkylation of 1,2,4-triazole with 4-nitrobenzyl halides and a variety of bases afforded the 1- and 4-alkylated isomers with a consistent regioselectivity of 90:10. Previously reported regiospecific alkylations of 1,2,4-triazole were re-examined and the quoted isomer ratios were shown to depend on the isolation procedure. The use of DBU as base in the alkylation of 1,2,4-triazole allows for a convenient and high yielding synthesis of 1- substituted-1,2,4-triazoles. (C) 2000 Elsevier Science Ltd.