244634-31-9

Usage

Uses

Used in Pharmaceutical Research:
N-((2R,3S)-3-AMINO-2-HYDROXY-4-PHENYLBUTYL)-N-ISOBUTYL-4-NITROBENZENE-1-SULFONAMIDE HYDROCHLORIDE is used as a research compound for exploring its potential as a drug candidate due to its unique molecular structure and functional groups.
Used in Drug Development:
In the pharmaceutical industry, N-((2R,3S)-3-AMINO-2-HYDROXY-4-PHENYLBUTYL)-N-ISOBUTYL-4-NITROBENZENE-1-SULFONAMIDE HYDROCHLORIDE is utilized for drug development, where its properties and interactions with biological targets are studied to assess its therapeutic potential.
Used in Therapeutic Applications:
N-((2R,3S)-3-AMINO-2-HYDROXY-4-PHENYLBUTYL)-N-ISOBUTYL-4-NITROBENZENE-1-SULFONAMIDE HYDROCHLORIDE may be employed as a therapeutic agent, pending further research into its efficacy and safety in treating specific medical conditions or diseases.

Upstream product

• 191226-98-9 [(1S,2R)-3-[(4-nitrophenylsulfonyl)(2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]carbamic acid tert-butyl ester 
• 160232-08-6 (2R,3S)-3-tert-butoxycarbonylamino-1-isobutylamino-4-phenyl-2-butanol 
• 98760-08-8 (1-oxiranyl-2-phenylethyl)carbamic acid tert-butyl ester 

Downstream Products

• 1415750-61-6 [(1S,2R)-3-[(4-aminophenylsulfonyl)(2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]amine hydrochloride 
• 206361-99-1 darunavir 
• 1233885-46-5 C₃₂H₄₅N₃O₁₁S 
• 1233884-93-9 (S)-{(R)-1-{3-[(10S,11R)-10-benzyl-11-hydroxy-15-methyl-13-(4-nitrophenylsulfonyl)-2,8-dioxo-7-oxa-3,9,13-triazahexadecyloxy]phenyl}-3-(3,4-dimethoxyphenyl)propyl} 1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carboxylate 
• 1233884-95-1 tert-butyl 4-[(2S,3R)-3-hydroxy-4-(N-isobutyl-4-nitrophenylsulfonamido)-1-phenylbutan-2-ylcarbamoyloxy]butane 

Relevant academic research and scientific papers

NOVEL SOLVATES OF DARUNAVIR

The present invention relates to novel solvates of Darunavir of Formula I.

NOVEL SOLVATES OF DARUNAVIR

The present invention relates to novel solvates of Darunavir of Formula (I).

PROTEASE INHIBITORS

Compounds useful as protease inhibitors are provided, as are methods of use and preparation of such compounds and compositions containing such compounds. In one embodiment, the compounds are useful for inhibiting HIV protease enzymes, and are therefore useful in slowing the proliferation of HIV.

Process for the synthesis of HIV protease inhibitors

An improved process for the synthesis of (3S)-tetrahydro-3-furyl N-[(1S,2R)-3 -(4-amino-N-isobutylbenzenesulphonamido)-1-benzyl-2-hydroxypropyl]carbamate comprising four steps form the compound of formula A and a novel intermediate thereto.