244634-31-9

Basic information

• Product Name: N-((2R,3S)-3-AMINO-2-HYDROXY-4-PHENYLBUTYL)-N-ISOBUTYL-4-NITROBENZENE-1-SULFONAMIDE HYDROCHLORIDE
• Synonyms: N-((2R,3S)-3-AMINO-2-HYDROXY-4-PHENYLBUTYL)-N-ISOBUTYL-4-NITROBENZENE-1-SULFONAMIDE HYDROCHLORIDE;N-[(2R,3S)-3-amino-2-hydroxy-4-phenylbutyl]-N-(2-methylpropyl)-4-nitro- Benzenesulfonamide hydrochloride (1:1);BenzenesulfonaMide,N-[(2R,3S)-3-aMino-2-hydroxy-4-phenylbutyl]-N-(2-Methylpropyl)-4-nitro-,hydrochloride (1:1);N-[(2R,3S)-3-Amino-2-hydroxy-4-phenylbutyl]-N-(2-methylpropyl)-4-nitrobenzenesulfonamide monohydrochloride
• CAS NO: 244634-31-9
• Molecular Formula: C₂₀H₂₇N₃O₅S*ClH
• Molecular Weight: 457.97
• Mol File: 244634-31-9.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-((2R,3S)-3-AMINO-2-HYDROXY-4-PHENYLBUTYL)-N-ISOBUTYL-4-NITROBENZENE-1-SULFONAMIDE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-((2R,3S)-3-AMINO-2-HYDROXY-4-PHENYLBUTYL)-N-ISOBUTYL-4-NITROBENZENE-1-SULFONAMIDE HYDROCHLORIDE(244634-31-9)
• EPA Substance Registry System: N-((2R,3S)-3-AMINO-2-HYDROXY-4-PHENYLBUTYL)-N-ISOBUTYL-4-NITROBENZENE-1-SULFONAMIDE HYDROCHLORIDE(244634-31-9)

Safety Data

• Hazardous Substances Data: 244634-31-9(Hazardous Substances Data)

Usage

General Description

The chemical N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutyl-4-nitrobenzene-1-sulfonamide hydrochloride is a compound with a complex molecular structure that consists of a sulfonamide group attached to a 4-nitrobenzene ring, with a hydrochloride salt. The compound features an amino group and a hydroxy group attached to a chiral carbon center, with an isobutyl and phenyl group linked to the sulfur atom. This chemical may be used in pharmaceutical research and applications, potentially as a drug candidate or for other therapeutic purposes. The specific properties, uses, and potential effects of this compound would require further investigation and study.

Upstream product

• 98760-08-8 (1-oxiranyl-2-phenylethyl)carbamic acid tert-butyl ester 
• 160232-08-6 (2R,3S)-3-tert-butoxycarbonylamino-1-isobutylamino-4-phenyl-2-butanol 
• 191226-98-9 [(1S,2R)-3-[(4-nitrophenylsulfonyl)(2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]carbamic acid tert-butyl ester 

Downstream Products

• 1415750-61-6 [(1S,2R)-3-[(4-aminophenylsulfonyl)(2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]amine hydrochloride 
• 206361-99-1 darunavir 
• 1233885-46-5 C₃₂H₄₅N₃O₁₁S 
• 1233884-93-9 (S)-{(R)-1-{3-[(10S,11R)-10-benzyl-11-hydroxy-15-methyl-13-(4-nitrophenylsulfonyl)-2,8-dioxo-7-oxa-3,9,13-triazahexadecyloxy]phenyl}-3-(3,4-dimethoxyphenyl)propyl} 1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carboxylate 
• 1233884-95-1 tert-butyl 4-[(2S,3R)-3-hydroxy-4-(N-isobutyl-4-nitrophenylsulfonamido)-1-phenylbutan-2-ylcarbamoyloxy]butane 

Relevant articles and documents

NOVEL SOLVATES OF DARUNAVIR

The present invention relates to novel solvates of Darunavir of Formula I.

PROTEASE INHIBITORS

Compounds useful as protease inhibitors are provided, as are methods of use and preparation of such compounds and compositions containing such compounds. In one embodiment, the compounds are useful for inhibiting HIV protease enzymes, and are therefore useful in slowing the proliferation of HIV.