244634-55-7Relevant academic research and scientific papers
Total synthesis and protein kinase activity of C(7) methyl derivatives of K252a
Wood, John L.,Petsch, Dejah T.,Stoltz, Brian M.,Hawkins, Elizabeth M.,Elbaum, Daniel,Stover, David R.
, p. 1529 - 1533 (2007/10/03)
Recent efforts in these laboratories have resulted in the development of a synthetic approach to C(7) alkyl analogs in the K252a class of indolocarbazole natural products. Synthesis of 7- (R)-methyl K252a (3a) and 7-(S)-methyl K252a (3b) will be described along with their activity against protein tyrosine kinases.
