24470-97-1Relevant academic research and scientific papers
Protolytic equilibria of picric acid in a mixture of protophobic and protophilic polar solvents non-donors of H-bonds
Ruzanova,Samoilovb,Genshc,Zevatskiia Yu.,Novoselovc
, p. 1153 - 1158 (2011)
A new differentiating medium for the study of prototropic equilibria is proposed: acetonitrile with a small addition of DMSO. From the dependence of the picric acid pKa on the content of DMSO in this medium the optimum composition of the mixture was found ensuring the stability of the pK a values with minimal addition of DSMO: 4 wt %. It was experimentally confirmed that the addition of water in an amount up to 0.1 wt % has virtually no effect on the measured pKa value in a mixture with the optimum composition. Pleiades Publishing, Ltd., 2011.
