244789-18-2

Usage

Uses

Used in Pharmaceutical Industry:
2-(2,6-Dimethylmorpholin-4-yl)ethanamine is used as a reagent in organic synthesis for the development of new pharmaceuticals. Its presence in the synthesis process contributes to the creation of various medicinal compounds, enhancing their efficacy and therapeutic potential.
Used in Agrochemical Industry:
In the agrochemical sector, 2-(2,6-Dimethylmorpholin-4-yl)ethanamine serves as an intermediate in the production of agrochemicals. Its role in this industry is crucial for the synthesis of compounds that help protect crops and enhance agricultural productivity.
Used in Dye and Pigment Production:
2-(2,6-Dimethylmorpholin-4-yl)ethanamine is also utilized in the production of dyes and pigments. Its chemical properties make it suitable for creating a range of colorants used in various industries, including textiles, plastics, and printing inks.
Overall, 2-(2,6-Dimethylmorpholin-4-yl)ethanamine's diverse applications across different industries highlight its importance in the development and production of chemicals and pharmaceuticals. Its presence in these fields is of significant interest to researchers and industries alike, as it contributes to the advancement of various products and technologies.

InChI:InChI=1/C8H18N2O/c1-7-5-10(4-3-9)6-8(2)11-7/h7-8H,3-6,9H2,1-2H3

Upstream product

• 141-91-3 2,6-dimethyl morpholine 
• 556053-92-0 2-[2-(2,6-dimethylmorpholin-4-yl)ethyl]isoindole-1,3-dione 
• 96042-30-7 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran 
• 141-91-3 cis-2,6-dimethylmorpholine 

Downstream Products

• 1286232-13-0 3-(3-chloro-5-methoxyphenyl)-N-(2-(2,6-dimethylmorpholino)ethyl)-4-(pyridin-4-yl)-1H-pyrazole-1-carboxamide 
• 1309606-01-6 3-(3-chloro-4-methoxyphenyl)-N-(2-(2,6-dimethylmorpholino) ethyl)-4-(pyridin-4-yl)-1H-pyrazole-1-carboxamide 
• 1352810-92-4 3-(4-chloro-3-methoxyphenyl)-N-(2-(2,6-dimethylmorpholino)ethyl)-4-(pyridin-4-yl)-1H-pyrazole-1-carboxamide 
• 1352811-10-9 C₂₄H₂₈ClN₅O₃ 
• 1226788-76-6 C₁₆H₂₁ClFN₃O₃ 

Relevant academic research and scientific papers

NITROGEN-CONTAINING FUSED CYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF

The present invention relates to a nitrogen-containing fused ring compound, a preparation method and use thereof. Specifically, the present invention relates to a compound having the structure of Formula (X), a stereoisomer, tautomer or mixture thereof, a pharmaceutically acceptable salt, co-crystal, polymorph or solvate thereof, or a stable isotope derivative, metabolite or prodrug thereof. The compound of the invention may have the structure of Formula (I) or Formula (II). These compounds are useful for the treatment of an abnormal cell proliferation disease (e.g., cancer). ????????R-L-R3?????(X)

Synthesis and pharmacological evaluation of new 1,2-dithiolane based antioxidants

Molecules containing a dithiolane moiety are widely investigated due to their antioxidant properties. The archetypal representative of this class of compounds is lipoic acid and indeed the lipoic acid-dihydrolipoic acid couple is part of the antioxidant defence system of the cell. In the course of a program aiming to find improved antioxidants effective in vivo, we designed, synthesised and pharmacologically investigated new lipoic acid analogs. The salient feature of these structures is the connection, via a thioamide or a thiocarbamate, of a 1,2-dithiolane moiety bearing a carbon chain and a N-alkyl-substituted morpholine ring. It was expected that the antioxidant and chelating properties of these functional groups combined with the basicity of the morpholine ring will impact on the antioxidant as well as on the partition and solubility characteristics of the compounds. Indeed in vitro and in vivo pharmacological investigation showed that these new molecules and especially those containing a thiocarbamate linker possess superior antioxidant properties compared with α-lipoic acid and to the amide or carbamate linker analogs. In particular, some of these compounds efficiently cross the blood brain barrier (BBB) thus providing efficient protection from lethality in a situation of induced oxidative stress. Moreover the absence of the 1,2-dithiolane moiety does not completely abolish antioxidant effects thus demonstrating that these compounds are distinct new chemical entities and not merely lipoic acid prodrugs. The chemical and pharmacological features of these new antioxidants are presented and discussed in the following paper.