2448-00-2

Usage

Uses

Used in Agricultural Applications:
Dicamba is used as a herbicide in the agricultural industry for the control of broadleaf weeds in various crops. Its selective nature allows it to target unwanted plants without causing harm to the desired crop species, making it a valuable tool for farmers to maintain crop health and productivity.
Despite the concerns regarding its potential to drift and affect non-target plants, dicamba remains a widely used product in agriculture due to its effectiveness in controlling specific types of weeds. Efforts to mitigate the environmental impact of dicamba include the development of formulations with lower volatility and the implementation of best management practices to minimize drift.

Upstream product

• 104-12-1 p-chlorphenylisocyanate 
• 541-73-1 1,3-Dichlorobenzene 
• 50-84-0 2,4 dichlorobenzoic acid 
• 106-47-8 4-chloro-aniline 
• 89-75-8 2,4-dichlorobenzoyl chloride 

Relevant academic research and scientific papers

Continuous flow photochemistry as an enabling synthetic technology: Synthesis of substituted-6(5: H)-phenanthridinones for use as poly(ADP-ribose) polymerase inhibitors

Methods utilizing continuous flow photochemistry, an enabling synthetic technology, have been developed for the generation of phenanthridinones via an intramolecular photochemical cyclization of 2-chlorobenzamides for the purposes of generating poly(ADP-ribose) polymerase inhibitors. Herein we report 16 examples of a single-step flow photocyclization which produces substituted phenanthridinones in yields up to 99%, while a two-step method leads directly to phenanthridinones from 2-chlorobenzoyl chlorides and anilines via a novel continuous flow amidation/photocyclization protocol. Overall, the flow photocyclization reactions typically progress in good to excellent yields, and in a superior fashion to analogous batch methods, greatly enabling the drug discovery process.

1,3,4-Oxadiazolethiol as Acyl-transfer Reagent in Acylation of Amines: A One-pot Reaction

Amines are acylated using 5-(2,4-dichlorophenyl)-1,3,4-oxadiazolethiol in the presence of diethyl chlorothiophosphate (DCTP) in good yield.