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(5alpha,17alpha)-3,3-difluoropregn-20-yn-17-ol is a synthetic steroid compound that is a derivative of pregnenolone. It contains two fluorine atoms at the 3rd position of the molecule and a hydroxyl group at the 17th position. It is a potent inhibitor of 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1), an enzyme that is involved in the biosynthesis of estrogen and testosterone.

2448-69-3

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2448-69-3 Usage

Uses

Used in Pharmaceutical Industry:
(5alpha,17alpha)-3,3-difluoropregn-20-yn-17-ol is used as a pharmaceutical agent for the treatment of hormone-related diseases such as breast cancer and prostate cancer. Its inhibitory effect on 17beta-HSD1 makes it a potential therapeutic option for these conditions.
Used in Contraceptive Development:
(5alpha,17alpha)-3,3-difluoropregn-20-yn-17-ol is used as a component in the development of contraceptives due to its ability to inhibit the biosynthesis of estrogen and testosterone, which play a role in fertility.
Used in Hormone Replacement Therapy:
(5alpha,17alpha)-3,3-difluoropregn-20-yn-17-ol is used as a hormone replacement therapy agent to help manage symptoms associated with hormonal imbalances, such as those experienced during menopause. Its ability to modulate hormone levels makes it a potential candidate for this application.

Check Digit Verification of cas no

The CAS Registry Mumber 2448-69-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,4,4 and 8 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 2448-69:
(6*2)+(5*4)+(4*4)+(3*8)+(2*6)+(1*9)=93
93 % 10 = 3
So 2448-69-3 is a valid CAS Registry Number.

2448-69-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (5S,8R,9S,10S,13S,14S,17R)-17-ethynyl-3,3-difluoro-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-ol

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2448-69-3 SDS

2448-69-3Upstream product

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