24480-44-2

Basic information

• Product Name: (20R)-3-Oxo-D:C-friedoolean-8-en-29-oic acid
• Synonyms: (20R)-3-Oxo-D:C-friedoolean-8-en-29-oic acid;Bryononic acid;(2R,4As,6as,8ar,10S,12as,14as,14br)-10-hydroxy-2,4A,6A,9,9,12A,14A-heptamethyl-1,2,3,4,4A,5,6,6A,7,8,8A,9,10,11,12,12A,13,14,14A,14B-eicosahydro-picene-2-carboxylic acid;Aids075058;Aids-075058
• CAS NO: 24480-44-2
• Molecular Formula: C30H48O3
• Molecular Weight: 456.70032
• Mol File: 24480-44-2.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 553.3°Cat760mmHg
• Flash Point: 302.5°C
• Appearance: /
• Density: 1.1g/cm³
• Vapor Pressure: 1.51E-14mmHg at 25°C
• Refractive Index: 1.557
• CAS DataBase Reference: (20R)-3-Oxo-D:C-friedoolean-8-en-29-oic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (20R)-3-Oxo-D:C-friedoolean-8-en-29-oic acid(24480-44-2)
• EPA Substance Registry System: (20R)-3-Oxo-D:C-friedoolean-8-en-29-oic acid(24480-44-2)

Safety Data

• Hazardous Substances Data: 24480-44-2(Hazardous Substances Data)

Usage

General Description

(20R)-3-Oxo-D:C-friedoolean-8-en-29-oic acid is a triterpenoid chemical compound that is derived from the organic compound, oleanolic acid. It belongs to the class of friedelane-type triterpenoids, and it is characterized by a 3-oxo group at the 20th carbon position and a carboxylic acid group at the 29th carbon position. (20R)-3-Oxo-D:C-friedoolean-8-en-29-oic acid has been studied for its potential pharmacological activities, including its anti-inflammatory and anti-cancer properties. It has shown significant cytotoxicity against cancer cells and has also exhibited potential anti-inflammatory effects by inhibiting the production of inflammatory mediators. Additionally, it has been investigated for its potential application as a novel drug candidate for the treatment of various diseases. Further research is needed to fully understand the pharmacological properties and potential therapeutic uses of this compound.

InChI:InChI=1/C30H48O3/c1-25(2)21-9-8-20-19(28(21,5)12-11-23(25)31)10-13-30(7)22-18-27(4,24(32)33)15-14-26(22,3)16-17-29(20,30)6/h21-23,31H,8-18H2,1-7H3,(H,32,33)/t21-,22+,23-,26+,27+,28+,29+,30-/m0/s1

Upstream product

• 24480-43-1 (2R,4aS,6aS,8aR,10S,12aS,14aS,14bR)-methyl 10-hydroxy-2,4a,6a,9,9,12a,14a-heptamethyl-1,2,3,4,4a,5,6,6a,7,8,8a,9,10,11,12,12a,13,14,14a,14b-icosahydropicene-2-carboxylate 
• 118797-73-2 3α-hydroxymultiflora-7,9(11)-dien-29α-oic acid 
• 76475-14-4 bryocoumaric acid 
• 143183-42-0 3-epibryonolol diacetate 
• 143183-45-3 D:C-friedo-olean-9(11)-ene-3α,29-diol diacetate 
• 143183-47-5 7-oxodihydrokarounidiol 
• 118117-33-2 karounidiol diacetate 
• 143183-46-4 3-epibryonolol 
• 143183-39-5 3-epibryonolic acid 
• 177354-94-8 (2R,4aS,6aS,8aR,10S,12aS,14aS,14bR)-10-hydroxy-2,4a,6a,9,9,12a,14a-heptamethyl-1,2,3,4,4a,5,6,6a,7,8,8a,9,10,11,12,12a,13,14,14a,14b-icosahydropicene-2-carboxylic acid 
• 76475-19-9 3α-p-acetoxycinnamyloxymultiflora-7,9(11)-dien-29α-oic acid 
• 143183-48-6 7-oxodihydrokarounidiol diacetate 
• 143183-44-2 D:C-friedo-olean-7-ene-3α,29-diol diacetate 

Downstream Products

• 177354-94-8 (2R,4aS,6aS,8aR,10S,12aS,14aS,14bR)-10-hydroxy-2,4a,6a,9,9,12a,14a-heptamethyl-1,2,3,4,4a,5,6,6a,7,8,8a,9,10,11,12,12a,13,14,14a,14b-icosahydropicene-2-carboxylic acid 

Relevant articles and documents

7-Oxodihydrokarounidiol [7-oxo-D:C-friedo-olean-8-ene-3α,29-diol], novel triterpene from Trichosanthes kirilowii

The structure of 7-oxodihydrokarounidiol [7-oxo-D:C-friedo-olean-8-ene-3α,29-diol], isolated from the seeds of Trichosanthes kirilowii (Cucurbitaceae), was determined by chemical correlation with karounidiol [D:C-friedo-oleana-7,9(11)-diene-3α,29-diol] from the same source. Two other natural products, viz. bryonolic acid (3β-hydroxy-D:C-friedo-olean-8-en-29-oic acid) and bryononic acid (3-oxo-D:C-friedo-olean-8-en-29-oic acid), were also correlated with karounidiol.