245-37-4

Upstream product

• 50890-67-0 4,5-Diazafluoren-9-one 
• 7291-22-7 perdeuteriopyridine 
• 1415222-47-7 (pentamethylcyclopentadienyl)₂Yb(4,5-diazafluorene) 
• 90299-47-1 5,5'-hydrazine-1,2-diylidene-bis(5H-pyrido[3',2':4,5]cyclopenta[1,2-b]pyridine) 
• 90299-45-9 4,5-diazafluorenone-9-hydrazone 

Downstream Products

• 272458-07-8 (9H-4,5-Diazafluoren-9-ylidene)-2,5-dimethylphenylmethane 
• 256512-10-4 9-(9H-4,5-Diazafluoren-9-ylphenylmethylene)-9H-fluorene 
• 256511-99-6 (9H-4,5-Diazafluoren-9-ylidene)phenylmethane 
• 256512-11-5 9-[(9H-4,5-Diazafluoren-9-ylidene)phenylmethyl]-9H-4,5-diazafluorene 
• 272458-08-9 9-[(9H-4,5-Diazafluoren-9-ylidene)-2,5-dimethylphenylmethyl]-9H-4,5-diazafluorene 
• 272458-15-8 2,7-Dibromo-9-[(9H-4,5-diazafluoren-9-ylidene)phenylmethyl]-9H-fluorene 
• 256512-12-6 9-[(9H-4,5-Diazafluoren-9-ylidene)-2,5-dimethylphenylmethyl]-2,7-dibromo-9H-fluorene 
• 204124-23-2 (4,5-diazafluorene-κN)bis[(2,3-η(2))-1,4-naphthoquinone]palladium(0) 
• 191738-47-3 bis[[μ-(2,3-η(2):5,6-η(2))]1,4-benzoquinone]-μ-(4,5-diazafluorene-κ(2)N,N')bis[palladium(0)] 
• 675599-96-9 9,9-dimethyl-4,5-diazafluorene 

Related news

A ruthenium(II) bipyridine complex containing a 4,5-Diazafluorene (cas 245-37-4) moiety: Synthesis, characterization and its applications in transfer hydrogenation of ketones and dye sensitized solar cells09/28/2019

The ruthenium(II) complex [Ru(bpy) 2 L](PF 6 ) 2 , where bpy is 2,2′-bipyridine and L is 1,5-dihydro-2-H-cyclopenta[1,2-b:5,4-b′]dipyridine-2-one, was synthesized from the reaction of cis-Ru(bpy) 2 Cl 2 ·2H 2 O with L, and isolated as the hexafl...detailed

Relevant academic research and scientific papers

Synthesis of 9,9-dialkyl-4,5-diazafluorene derivatives and their structure-activity relationships toward human carcinoma cell lines

A homologous set of 9,9-dialkyl-4,5-diazafluorene compounds were prepared by alkylation of 4,5-diazafluorene with the appropriate alkyl bromide and under basic conditions. The structures of these simple organic compounds were confirmed by spectroscopic techniques (FTIR, NMR, and FABMS). Their biological effects toward a panel of human carcinoma cells, including Hep3B hepatocellular carcinoma, MDAMB-231 breast carcinoma, and SKHep-1 hepatoma cells, were investigated; a structure-activity correlation was established with respect to the length of the alkyl chain and the fluorene ring structure. The relationship between the mean potency [log(1/IC50)] and alkyl chain length was systematically studied. The results show that compounds with butyl, hexyl, and octyl chains exhibit good growth inhibitory effects toward these three human carcinoma cell lines, and the 9,9-dihexyl-4,5-diazafluorene further exhibits antitumor activity in athymic nude mice Hep3B xenograft models. For the structurally related dialkylfluorenes that lack the diaza functionality, in vitro cytotoxicity was not observed at clinically relevant concentrations.

Polyaza Cavity Shaped Molecules. 5. Annelated Derivatives of 2,2'-Bipyridine

Friedlaender condensation of β-aminoacrolein with percenta-oxo-2,3-cycloalkenopyridines or thermolysis of the O-allyloximes derived from these ketones leads to the formation of 3,3'-bridged-2,2'-bipyridines 2a-d.Reaction of 2a-d with 1,2-dibromoethane giv

SELECTIVE PERTURBATION OF LIGAND FIELD EXCITED STATES IN POLYPYRIDINE RUTHENIUM(II) COMPLEXES.

A new bipyridine-type ligand which allows the selective perturbation of ligand field (LF) excited-state energies is introduced. Any metal-to-ligand charge-transfer (MLCT) excited states occur at nearly the same energy as in the bipyridine complex. The syntheses of the corresponding ruthenium(II) complexes and their photophysical properties are reported. The results clearly support a current model for the excited-state behavior of polypyridine complexes in which the lowest MLCT decays by thermal population of a higher lying LF state. This method of selective LF-state perturbation nicely complements the perturbation of MLCT states achieved by modification of the ligand's reduction potential.

Design, synthesis of 4,5-diazafluorene derivatives and their anticancer activity via targeting telomeric DNA G-quadruplex

In our work, 19 novel 4,5-diazafluorene derivatives (11a-d, 12a-d, 13a-d, 14a-c, 15c, 16a-c) bearing a 1,3-disubstituted pyrazol/thioxothiazolidinone or thioxothiazolidinone-oxadiazole moieties were designed, synthesized, preliminarily explored for their

4,5-diazafluorene derivative, preparation method and applications thereof

The invention relates to a 4,5-diazafluorene derivative, a preparation method and applications thereof, wherein a 1,10-phenanthroline monohydrate and potassium permanganate are subjected to an oxidizing reaction to obtain a 4,5-diazafluoren-9-one intermed

NOVEL COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME

Disclosed are a compound for an organic electroluminescent device and an organic electroluminescent device comprising the same. Thus, provided is a compound for an organic electroluminescent device and an organic electroluminescent device comprising the s

NOVEL COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME

In the present invention, disclosed are a compound of an organic electroluminescent device denoted by structural formula 1 and an organic electroluminescent device including the same. In the present invention, provided are a compound of an organic electroluminescent device which has outstanding electrical stability and electron and hole transport performance and exhibits high triplet energy level, thereby being used as hosts, hole transport materials and electron transport materials to increase light emitting efficiency of phosphorescent luminescent materials, and an organic electroluminescent device.

INDENOTRIPHENYLENE DERIVATIVES AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME

The present invention discloses a new indenotriphenylene derivatives and organic light emitting device using the derivatives. The organic light emitting device employing new indenotriphenylene derivatives as host material can lower driving voltage, prolong half-lifetime, increasing efficiency. The new indenotriphenylene derivatives are represented by the following formula (A): Wherein A1, A2 are substituted or unsubstituted fused ring hydrocarbon units with one to five rings. Preferably A1, A2 are phenyl group, naphthyl group, anthracenyl group, pyrenyl group, chrysenyl group. Perylenyl group. R1 to R4 are identical or different. R1 to R4 are independently selected from the group consisting of a hydrogen atom, a halide, alkyl group having 1 to 20 carbon atoms, a substituted or unsubstituted aryl group having 6 to 30 carbon atoms, a substituted or unsubstituted aralkyl group having 6 to 30 carbon atoms, a substituted or unsubstituted heteroaryl group having 6 to 30 carbon atoms. X is selected from carbon atom or nitrogen atom.

Thermal dihydrogen elimination from Cp*2Yb(4,5- diazafluorene)

The reaction of 4,5-diazafluorene with Cp*2Yb(OEt 2), where Cp* is pentamethylcyclopentadienyl, affords the isolable adduct Cp*2Yb(4,5-diazafluorene) (1), which slowly eliminates H2 to form Cp*2Yb(4,5-diazafluorenyl) (2); the net reaction is therefore 1 → 2 + H?. The ytterbium atom in 1 is shown to be intermediate valent by variable-temperature LIII-edge X-ray absorption near-edge (XANES) spectroscopy, consistent with its low effective magnetic moment (μeff). The experimental studies are supported by complete active space self-consistent field (CASSCF) calculations, showing that two open-shell singlets lie below the triplet state. The two open-shell singlets are calculated to be multiconfigurational and closely spaced, in agreement with the observed temperature dependence of the XANES and χ data, which are fit to a Boltzmann distribution. A mechanism for dihydrogen formation is proposed on the basis of kinetic and labeling studies to involve the bimetallic complex (Cp*2Yb)2(4,5- diazafluorenyl)2, in which the heterocyclic amine ligands are joined by a carbon-carbon bond at C(9)-C(9′).

DIAZAFLUORENE COMPOUND

The present invention provides a novel diazafluorene compound for manufacturing a 4,5-diazafluorene derivative. The diazafluorene compound is represented by the general formula (1): wherein R1 and R2 each represent a hydrogen atom, a