245114-71-0Relevant academic research and scientific papers
A divergent method for preparing 1-aryl- and 1,3-diarylazulenes from ethyl 3-(cyclohepta-1,3,5-trien-1-yl)-3-oxopropionate
Oda, Mitsunori,Kajioka, Takanori,Haramoto, Kanae,Miyatake, Ryuta,Kuroda, Shigeyasu
, p. 1349 - 1353 (1999)
The 3-aryl substituted 1,2,3,8-tetrahydroazulen-1-ones 3, prepared by the Knoevenagel condensation of ethyl 3-(cyclohepta-1,3,5-trien-1-yl)-3- oxopropionate (6) with arylaldehydes and subsequent Nazarov cyclization, were efficiently transformed into 1-aryl- and 1,3-diarylazulenes in a few steps.
