245115-73-5

Basic information

• Product Name: cyclo[Ala-Pro-Phe-Ser(oxaz)-Thr(rprenyl)-Ser(rprenyl)Ile]
• Synonyms: cyclo[Ala-Pro-Phe-Ser(oxaz)-Thr(rprenyl)-Ser(rprenyl)Ile]
• CAS NO: 245115-73-5
• Molecular Weight: 822.015
• Mol File: 245115-73-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: cyclo[Ala-Pro-Phe-Ser(oxaz)-Thr(rprenyl)-Ser(rprenyl)Ile](CAS DataBase Reference)
• NIST Chemistry Reference: cyclo[Ala-Pro-Phe-Ser(oxaz)-Thr(rprenyl)-Ser(rprenyl)Ile](245115-73-5)
• EPA Substance Registry System: cyclo[Ala-Pro-Phe-Ser(oxaz)-Thr(rprenyl)-Ser(rprenyl)Ile](245115-73-5)

Safety Data

• Hazardous Substances Data: 245115-73-5(Hazardous Substances Data)

Upstream product

• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 16874-59-2 L-phenylalanyl-L-serine methyl ester hydrochloride 
• 186023-44-9 Fmoc-Ala-Pro-OH 
• 245115-66-6 (S)-2-[(2S,3R)-2-Benzyloxycarbonylamino-3-(1,1-dimethyl-allyloxy)-butyrylamino]-3-(1,1-dimethyl-allyloxy)-propionic acid methyl ester 
• 245115-64-4 (S)-2-Amino-3-(1,1-dimethyl-allyloxy)-propionic acid methyl ester 
• 245115-71-3 Fmoc-Ala-Pro-Phe-Ser(TBS)-Thr(rprenyl)-Ser(rprenyl)-Ile(OMe) 
• 267876-85-7 C₅₀H₈₃N₇O₁₁Si 
• 267876-86-8 2-[2-[2-[2-(2-{[1-(2-amino-propionyl)-pyrrolidine-2-carbonyl]-amino}-3-phenyl-propionylamino)-3-(tert-butyl-dimethyl-silanyloxy)-propionylamino]-3-(1,1-dimethyl-allyloxy)-butyrylamino]-3-(1,1-dimethyl-allyloxy)-propionylamino]-3-methyl-pentanoic acid 
• 245115-70-2 Fmoc-Ala-Pro-Phe-Ser(TBS)-OBn 
• 267876-92-6 Fmoc-Ala-Pro-Phe-OBn 
• 245115-67-7 Cbz-Thr(rprenyl)-Ser(rprenyl)-Ile-OMe 
• 267876-84-6 Fmoc-Ala-Pro-Phe-OH 
• 245115-69-9 Fmoc-Ala-Pro-OBn 
• 245115-68-8 (2S,3S)-2-[(S)-2-[(2S,3R)-2-Amino-3-(1,1-dimethyl-allyloxy)-butyrylamino]-3-(1,1-dimethyl-allyloxy)-propionylamino]-3-methyl-pentanoic acid methyl ester 

Downstream Products

• 267877-02-1 cyclo[Ala-Pro-PheΨ{(C=S)NH}-Ser-Thr(rprenyl)-Ser(rprenyl)Ile] 
• 268215-68-5 cyclo[Ala-Pro-Phe-Ser(thiaz)-Thr(rprenyl)-Ser(rprenyl)Ile] 

Relevant articles and documents

Total synthesis of trunkamide A, a novel thiazoline-based prenylated cyclopeptide metabolite from Lissoclinum sp.

Full details of a total synthesis of the doubly prenylated cyclic peptide trunkamide A of marine origin, and also its C45 epimer, are described.

Total synthesis of the putative structure of the marine metabolite trunkamide A

The structure assigned to trunkamide A, a cycloheptapeptide alkaloid isolated from the colonial ascidian Lissoclinum sp., was prepared via segment condensations and an efficient oxazoline-thiazoline interconversion. The novel reverse prenylated serine and