245122-91-2

Upstream product

• 766-97-2 4-n-methylphenylacetylene 
• 6630-33-7 ortho-bromobenzaldehyde 
• 189008-33-1 2-[2-(4-methylphenyl)ethynyl]benzaldehyde 

Downstream Products

• 189008-33-1 2-[2-(4-methylphenyl)ethynyl]benzaldehyde 
• 1205555-56-1 4-iodo-3-p-tolyl-1H-isochromene 
• 64421-13-2 1-(4-methylbenzylidene)-1,3-dihydroisobenzofuran 
• 1620151-60-1 6a-(p-tolyl)-5,6a-dihydroisochromeno[3,4-b]chromene 
• 1448450-02-9 N,N-dimethyl-4-((Z)-((Z)-3-(4-methylbenzylidene)isobenzofuran-1(3H)-ylidene)methyl)aniline 
• 1246831-55-9 (Z)?1?(4?methylbenzylidene)?1,3?dihydroisobenzofuran 
• 67237-87-0 3-(4-methylphenyl)isoquinoline 

Relevant academic research and scientific papers

Regio- and stereoselective intramolecular hydroalkoxylation of aromatic alkynols: an access to dihydroisobenzofurans under transition-metal-free conditions

An efficient, transition-metal-free method to synthesize dihydroisobenzofuran derivatives via intramolecular hydroalkoxylation of aromatic alkynols with the promotion of cesium carbonate has been developed. The reaction proceeds regioselectively with exclusive formation of 5-exo-dig product, and only Z-isomer of the new generated double bond is observed. This new protocol features with milder reaction conditions, more convenient operation and satisfactory selectivities.

Construction of Six-Membered Silacyclic Skeletons via Platinum-Catalyzed Tandem Hydrosilylation/Cyclization with Dihydrosilanes

Catalytic silicon-carbon or silicon-heteroatom bond-forming hydrosilylation has become increasingly important in synthetic chemistry, catalysis and organosilicon chemistry. Herein we report a platinum-catalyzed one-pot and tandem hydrosilylation/cyclization of OH-containing alkynes with dihydrosilanes, allowing for facile synthesis of six-membered organosilicon compounds, including silyloxycycles and cyclic siloxanes in high yields and with good stereoselectivities. (Figure presented.).