245126-95-8

Basic information

• Product Name: PIP2
• Synonyms: PHOSPHATIDYLINOSITOL 4,5-BIPHOSPHATE, AMMONIUM SALT;PHOSPHATIDYLINOSITOL, 4,5-BISPHOSPHATE, AMMONIUM SALT;PIP2;PIP2, TRIAMMONIUM SALT, BOVINE;PIP2, TRIAMMONIUM SALT, CALF BRAIN;L-ALPHA-PHOSPHATIDYL-D-MYO-INOSITOL-4,5-BISPHOSPHATE, TRIAMMONIUM SALT;L-ALPHA-PHOSPHATIDYL-D-MYO-INOSITOL-4,5-BISPHOSPHATE, TRIAMMONIUM SALT, BOVINE;L-ALPHA-PHOSPHATIDYL-D-MYO-INOSITOL-4,5-BISPHOSPHATE, TRIAMMONIUM SALT, BOVINE BRAIN
• CAS NO: 245126-95-8
• Molecular Formula: C47H85O19P3
• Molecular Weight: 1047.087683
• Mol File: 245126-95-8.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 1034.8°C at 760 mmHg
• Flash Point: 579.6°C
• Appearance: /
• Density: 1.25g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.538
• Storage Temp.: -70°C
• PKA: 1.43±0.50(Predicted)
• CAS DataBase Reference: PIP2(CAS DataBase Reference)
• NIST Chemistry Reference: PIP2(245126-95-8)
• EPA Substance Registry System: PIP2(245126-95-8)

Safety Data

• Hazardous Substances Data: 245126-95-8(Hazardous Substances Data)

Usage

Description

PIP2, also known as L-alpha-Phosphatidylinositol-4,5-bisphosphate, is a crucial phospholipid found in the cell membrane. It plays a significant role in various cellular processes, including signal transduction and membrane trafficking. PIP2 is involved in the regulation of ion channels and enzymes, making it a vital component in cellular function.

Uses

Used in Diagnostic Applications:
PIP2 is used as a diagnostic biomarker for various diseases, particularly in the field of cancer research. Its levels can indicate the presence or progression of certain types of cancer, aiding in early detection and treatment planning.
Used in Cancer Therapy:
In the pharmaceutical industry, PIP2 serves as a target for cancer therapy. By modulating the levels or activity of PIP2, researchers can develop drugs that interfere with cancer cell signaling pathways, potentially leading to the inhibition of tumor growth and the enhancement of existing cancer treatments.
Used in Research and Development:
In the biotechnology and academic research sectors, PIP2 is utilized as a key molecule for understanding cellular processes and the development of new therapeutic strategies. Its role in signal transduction and membrane trafficking makes it an essential tool for studying the underlying mechanisms of various diseases and conditions.

InChI:InChI=1/C47H85O19P3/c1-3-5-7-9-11-13-15-17-19-20-22-24-26-28-30-32-34-36-41(49)63-39(37-61-40(48)35-33-31-29-27-25-23-21-18-16-14-12-10-8-6-4-2)38-62-69(59,60)66-45-42(50)43(51)46(64-67(53,54)55)47(44(45)52)65-68(56,57)58/h11,13,17,19,22,24,28,30,39,42-47,50-52H,3-10,12,14-16,18,20-21,23,25-27,29,31-38H2,1-2H3,(H,59,60)(H2,53,54,55)(H2,56,57,58)/b13-11-,19-17-,24-22-,30-28-/t39-,42-,43+,44+,45-,46-,47-/m1/s1