24525-01-7

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
9-ethyl-9H-carbazole-3-sulfonyl chloride is used as a key intermediate in the synthesis of various pharmaceuticals and agrochemicals. Its ability to introduce carbazole moieties into different organic molecules makes it a valuable component in the development of new drugs and pesticides.
Used in Organic Synthesis:
As a reagent in organic synthesis, 9-ethyl-9H-carbazole-3-sulfonyl chloride is used to introduce carbazole moieties into different organic molecules. Its strong electrophilic properties allow for efficient reactions, contributing to the synthesis of a wide range of organic compounds.
Used in Research and Development:
Due to its unique chemical properties, 9-ethyl-9H-carbazole-3-sulfonyl chloride is widely utilized in the research and development of new materials and compounds in various industries. Its versatility as an intermediate enables the exploration of novel applications and advancements in chemical synthesis.

Upstream product

• 802034-95-3 9-ethyl-carbazole-3-sulfonic acid 
• 86-74-8 9H-carbazole 
• 86-28-2 N-ethylcarbazole 

Downstream Products

• 19507-40-5 9-Ethyl-9H-carbazole-3-sulfonic acid (4-methoxy-phenyl)-amide 

Relevant academic research and scientific papers

Synthesis and spectral studies of 2-[(N-ethyl carbazole)-3-sulfonyl ethylenediamine]-1-N,N-2-(2-methypyridy) as a fluorescence probe for Zn 2+

A novel Zn2+ fluorescence probe, 2-[(N-ethyl carbazole)-3-sulfonyl ethylenediamine]-1-N,N-bis(2-methypyrbidy), was designed and synthesized via simple steps, and its structure was confirmed by IR and 1H NMR. The probe gives significant fluorescence enhancement immediately following Zn2+ addition at neutral pH and exhibits improved selectivity for Zn2+ compared to the other metal ions in aqueous solution. The spectra and fluorescence quantum yield of the synthesized compound were carefully investigated by UV-vis absorption and fluorescence spectra in various solvents.

Novel pyridinyl and pyrimidinylcarbazole sulfonamides as antiproliferative agents

A series of azaheterocyclic carbazole sulfonamides was synthesized and evaluated for antiproliferative activity. The most potent compounds N-(2,6-dimethoxypyridine-3-yl)-9-ethyl and 9-methylcarbazole-3-sulfonamide (13 and 14) gave significant cytotoxicity (IC50 = 122 and 101 nM). Compound 13 displayed submicromolar activities against seven human tumor cell lines. The SARs of this series of sulfonamides which includes the influence of azaheterocycle rings, sulfonamide linkage, and the carbazole ring are described.