24539-57-9

Usage

Uses

Used in Enzymatic Hydrolysis Studies:
Monohexyl Phthalate is used as a substrate for characterizing human salivary esterase in enzymatic hydrolysis. This application helps researchers understand the enzyme's activity and its role in the breakdown of certain compounds in the human body.
Used in Chemical Research:
As a phthalate ester, Monohexyl Phthalate is used as a research compound in various chemical studies. Its properties and reactivity make it a valuable tool for understanding the behavior of similar compounds and their potential applications in different industries.
Used in Industrial Applications:
While the provided materials do not explicitly mention specific industrial applications, phthalate esters like Monohexyl Phthalate are generally used as additives in the plastics industry, particularly in the production of polyvinyl chloride (PVC). They are added to increase the flexibility, durability, and workability of the material.

InChI:InChI=1/C14H18O4/c1-2-3-4-7-10-18-14(17)12-9-6-5-8-11(12)13(15)16/h5-6,8-9H,2-4,7,10H2,1H3,(H,15,16)

Upstream product

• 85-44-9 phthalic anhydride 
• 111-27-3 hexan-1-ol 

Downstream Products

• 302776-68-7 n-hexyl 2-(4-diethylamino-2-hydroxybenzoyl)benzoate 

Relevant academic research and scientific papers

Synthesis method of ultraviolet absorber UVA Plus

The invention discloses a synthesis method of an ultraviolet absorber UVA Plus. The method comprises the following steps: step 1, carrying out esterification reaction on phthalic anhydride and n-hexanol to obtain an intermediate monohexyl phthalate without other solvents, enabling the yield to reach over 99%, and enabling the intermediate to be directly subjected to the next step of reaction without refining; step 2, performing an acylation reaction on 3-hydroxy-N, N-diethylaniline and the intermediate monohexyl phthalate under the catalysis of a composite catalyst to prepare an ultraviolet absorber UVA Plus product, enabling the yield to be over 90%. The synthesis method has the advantages of easily available raw materials, easy refining and purification of the product, high yield, low production cost, and suitableness for industrial production.

Ecotoxicity and biodegradation of phthalate monoesters

Little is known about the fate and the effects of phthalic acid monoesters. Various of these monoesters ranging from n-butyl to isononyl monoester have been evaluated in respect to their biodegradation behaviour and their acute aquatic toxicity. All esters are readily biodegradable, achieving degradation rates of 90% and more. The acute toxicity values strongly depend on the carbon chain length of the alcohol moiety. The short chain specimen have LC/EC 50 around and above 100 mg/l, with values levelling off to around 30 mg/l for the isononyl monoester.