24539-99-9Relevant academic research and scientific papers
Aminotetralone Analogues of Ketamine: Synthesis and Evaluation of Hypnotic and Locomotor Properties in Mice
Yang, David J.,Davisson, John N.
, p. 1361 - 1365 (2007/10/02)
Ketamine and phencyclidine are structurally similar compounds that share many pharmacological actions, some of which are similar to the phenethylamines amphetamine and cathione.In order to integrate structural features of ketamine and cathinone, two groups of analogues, which are more conformationally restricted compared to the parent compounds, were synthesized for biological evaluation.These included 1-amino-1-methyl-2-tetralone and 2-amino-2-methyl-1-tetralone was well as several N-substituted derivatives of these molecules.Locomotor activity testing in mice revealed that 2-amino-2-methyl-1-tetralone caused an increase in locomotor activity while 1-amino-1-methyl-2-tetralone depressed soontaneous locomotor activity.None of the compounds produced hypnosis or profound ataxia.
Imidazoisoindolediones and the use thereof as herbicidal agents
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, (2008/06/13)
The invention relates to novel imidazoisoindoledione compounds including the optical isomers thereof. This invention also relates to a method for the control of undesirable plant species with the imidazoisoindolediones and their optical isomers, and further, to a process for the preparation of the compounds.
Dihydroimidaz oisoindolediones and the use thereof as herbicidal agents
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, (2008/06/13)
The invention relates to novel dihydroimidazoisoindoledione compounds and the optical and stereo isomers thereof. This invention also relates to a method for the control of undesirable plant species with the dihydroimidazoisoindolediones and their optical and stereo isomers, and further, to a process for the preparation of the compounds.
